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ハロゲノフェニルグルコシド類の放射線増感に関する研究 : m-ヨードフェニルグルコシドの放射線増感効果に対するポリアミンの影響
http://hdl.handle.net/10076/6841
http://hdl.handle.net/10076/684117bcf4e2-80d9-425b-86ac-62a0a043e43b
名前 / ファイル | ライセンス | アクション |
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AN002343370007206.pdf (363.3 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2007-08-20 | |||||
タイトル | ||||||
言語 | ja | |||||
タイトル | ハロゲノフェニルグルコシド類の放射線増感に関する研究 : m-ヨードフェニルグルコシドの放射線増感効果に対するポリアミンの影響 | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
小宮, 孝志
× 小宮, 孝志× 山田, 哲也× 升井, 洋至× 樋廻, 博重 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 嫌気的条件下での放射線照射においてm-IPGによりE.coli B の致死作用および核酸合成阻容作用が共に増強された。照射によるバクテリオファージØX174の不活化のm-IPG添加効果をみると,1mM m-IPGの添加lにより放射線によるファージ不活化を大きく抑制した。更に,m-IPGの濃度を増すと徐々に無添加の効果に近づいた。m-IPGの放射線増感作用に対するポリアミン(putrescune, spermidine および spermine)の添加効果を調べたけっか,いずれのポリアミンもE.coli B に対する照射中のm-IPGによる致死作用および核酸合成阻害作用の増感効果を抑制した。この効果はポリアミンによりE.coli B の細胞膜が安定したことによるものと思われる。 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Both lethal and inhibition effects of E.coli B were sensitized by m-IPG in the anaerobic condition during X-ray irradition. The additional effect of m-IPG on radiation inactivation of bacterio-phage ØX174 was examined. It was found that the radiation inactivation was reduced greatly by addition of 1mM of m-IPG. Then, with increase of concentration of m-IPG more than 1mM, the radiosensitization effect reached the elevel of no additive. Effects of polyamines such as putrescine, spermindine, and spermine on the radiosensitization of m-IPG were examined. All the polyamines reduced radiosensitizing effect on the lethality and inhibition of DNA synthesis of E.coli B by m-IPG. This effect may be considered to be due to stabilizing of the cell membrane of E.coli B. | |||||
書誌情報 |
三重大學農學部學術報告 = The bulletin of the Faculty of Agriculture, Mie University 巻 72, p. 99-103, 発行日 1986-03-01 |
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ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0462-4408 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00234337 | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
その他のタイトル | ||||||
en | ||||||
Radiosensitization of Halogenophenyl β-D-Glucosides : Effects of Polyamines on Radiosensitization of m-Iodophenyl β-D-Glucoside | ||||||
出版者 | ||||||
出版者 | 三重大学農学部 | |||||
ノート | ||||||
Agropedia提供データ | ||||||
資源タイプ(三重大) | ||||||
Departmental Bulletin Paper / 紀要論文 |