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長期入院がん患児のディフィシル関連下痢症の予防ケアに関する教育プログラムの開発
http://hdl.handle.net/10076/13742
http://hdl.handle.net/10076/1374295aeab4f-2555-4bda-b9b9-856a7da3ab6e
名前 / ファイル | ライセンス | アクション |
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30K16863.pdf (376.3 kB)
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Item type | 報告書 / Research Paper(1) | |||||
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公開日 | 2014-03-10 | |||||
タイトル | ||||||
言語 | ja | |||||
タイトル | 長期入院がん患児のディフィシル関連下痢症の予防ケアに関する教育プログラムの開発 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 感染予防看護 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 長期入院 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 小児がん | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Clostridium difficile | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 予防ケア | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 教育プログラム | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_18ws | |||||
資源タイプ | research report | |||||
著者 |
村端, 真由美
× 村端, 真由美 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 血液腫瘍疾患で抗がん薬治療を受けた5-15歳の長期入院中のがん患児を対象に、糞便中の毒素検出、C. difficile分離培養、分離菌株における毒素産生パターンの同定、Polymerase chain reaction ribotypingによる解析、療養環境におけるC. difficile分布と伝播経路に関する調査をした。15名中13名からC. difficileが分離され、そのうち2名がC. difficile感染症と診断された。PCR ribotyping解析結果から、10名の患者間で4タイプの菌株が認められ、水平伝播の可能性が示唆された。長期入院がん患児の入院する小児病棟において、療養環境のC. difficileによる汚染状態を調査した。のべ502ヶ所を調べ、39ヶ所から39株、18タイプのC. difficileが分離された。血液腫瘍疾患で初めて抗腫瘍薬治療を受けた5-15歳の患児15名中13名から分離した19株と療養環境から分離した39株、計58株をPCR ribotypingにより、比較した結果、2名の患児の糞便からの分離菌株と療養環境からの分離菌株が一致した。療養環境から患児、患児から療養環境へとC. difficileが伝播し、がん患児においても医療関連感染を起こす可能性が示唆された。 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We investigated intestinal colonization by C. difficile in children undergoing antineoplastic chemotherapy. The environmental surfaces of the pediatric ward where they were hospitalized were sampled and examined for the presence of C. difficile.C. difficile was recovered from 13 of the 15 children examined, and 2 of them were given the diagnosis of C. difficile infection and treated by vancomycin. C. difficile isolates were analyzed by PCR ribotyping. Ten patients had four PCR ribotype, which indicates nosocomial spreading in the ward. A total of 502 environmental surfaces were examined and 39 were positive for C. difficile. The 39 C. difficile isolates were classified into 18 different PCR ribotypes. The same PCR ribotype was recovered from stool specimens of 2 patients as well as from environmental surfaces of their room. These findings indicate that environmental contamination may contribute to C. difficile transmission among pediatric cancer patients. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 平成21~23年度科学研究費補助金(若手研究(B))研究成果報告書 | |||||
書誌情報 |
発行日 2012-04-27 |
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フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
その他のタイトル | ||||||
Development of an Educational Program Regarding the Prevention of Clostridium difficile Infection for Pediatric Cancer Patients | ||||||
出版者 | ||||||
出版者 | 三重大学 | |||||
科研費番号 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 21792283 | |||||
資源タイプ(三重大) | ||||||
Kaken / 科研費報告書 |