2026-03-06T15:32:46Z https://mie-u.repo.nii.ac.jp/oai

oai:mie-u.repo.nii.ac.jp:02000078 2023-10-17T01:55:37Z 334:608:618:1336

Long-term course of the changes in the nipple position after breast-conserving surgery Kimoto, Mao キモト, マオ 木本, 真緒 open access Breast-conserving surgery Oncoplastic breast surgery Nipple position application/pdf Purpose: Even if favorable cosmetic outcomes are obtained shortly after breast conserving surgery (BCS), cosmetic changes may occur up to several years after BCS. In the present study, we evaluated cosmetic changes while focusing on changes in the nipple position after BCS. Methods: We examined the long-term course of changes in the nipple position overtime after BCS using the proportion of the distance between the sternal notch and nipple (PDSN) in 196 patients. We also evaluated risk factors for long-term nipple position changes. Results: The median follow-up period was 9.9 years. Nipple position changes occurred within eight years after BCS and seemed to plateau beyond that point. The body mass index (BMI), breast size, proportion of excision volume and axillary treatment were significantly associated with the nipple position changes within one to five years after BCS. The BMI, breast size, axillary treatment, chemotherapy and hormonal therapy were significantly associated with the nipple position changes within five to eight years after BCS. Conclusions: After BCS, the nipple position changes occur within about eight years. Obesity, large breast size, large excision volume, axillary treatment, chemotherapy and hormone therapy were factors that affected the treated breast shrinkage and increase in the left-right difference after BCS. 本文/Department of Breast Surgery, Mie University School of Medicine, Tsu, Mie, Japan 35p 三重大学 2022-09-21 eng doctoral thesis VoR http://hdl.handle.net/10076/0002000078 https://mie-u.repo.nii.ac.jp/records/2000078 乙医学第1077号 博士(医学) 2022-09-21 14101 三重大学 https://mie-u.repo.nii.ac.jp/record/2000078/files/2022DM0916.pdf application/pdf 747 KB 2023-09-06