2026-03-15T14:38:58Z https://mie-u.repo.nii.ac.jp/oai

oai:mie-u.repo.nii.ac.jp:02000337 2024-02-06T01:23:13Z 334:608:618:1694066935734

Prognostic Impact of Peak Aortic Jet Velocity on Patients With Acute Myocardial Infarction Mizutani, Hana ミズタニ, ハナ 水谷, 花菜 Acute myocardial infarction Aortic valve stenosis Prognosis 三重大学 博士(医学) application/pdf Background: Aortic valve stenosis (AS) leads to increased cardiovascular mortality and morbidity, and recent studies reported that even mild-to-moderate AS was associated with poor prognosis in the general population. This study investigated the prognostic impact of mild or moderate AS, defined as 2.0m/s ≤ peak aortic jet velocity (Vmax) ≤3.9m/s using echocardiography in acute myocardial infarction (AMI) patients. Methods and Results: This study enrolled 3,049 AMI patients using data from the Mie ACS registry. Patients were divided into 2 groups according to Vmax: Group 1: Vmax <2.0m/s and/or visually intact aortic valve in which all 3 leaflets are fully and evenly open; Group 2: 2.0m/s ≤ Vmax ≤ 3.9m/s. There were 2,976 patients in Group 1and 73 patients in Group 2. The Group 2 patients were older, had a higher percentage of males and had lower body mass index and Killip ≥2 than the Group 1 patients. Angiographic data, door-to-balloon time, and mechanical support were not different between the 2 groups. The Group 2 patients demonstrated a significantly higher all-cause mortality rate (P<0.01) and composite of cardiovascular death and heart failure hospitalization (P<0.01), and Kaplan-Meier analysis showed the same tendency in propensity score-matched patients. Conclusions: The present study revealed that mild or moderate AS based on Vmax is associated with poor prognosis following AMI. 本文/Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu 8p doctoral thesis 三重大学 2023-09-25 2023-09-25 application/pdf 甲医学第2210号 https://mie-u.repo.nii.ac.jp/record/2000337/files/2023DM0920.pdf http://hdl.handle.net/10076/0002000337 https://mie-u.repo.nii.ac.jp/records/2000337 eng 10.1253/circj.CJ-22-0217 open access