@phdthesis{oai:mie-u.repo.nii.ac.jp:00011324, author = {Kumagai, Naoto and 熊谷, 直人}, month = {Mar}, note = {application/pdf, We enrolled 196 patients with hypertension who were already being treated with free-drug combinations of angiotensin-II receptor blocker (ARB) and amlodipine. The free-drug combinations of ARB and amlodipine were replaced with the same dose of the fixed-dose combinations. The average home blood pressure (BP) in all patients receiving fixed-dose combinations was significantly lower than those receiving fixed-dose combinations (131±10/75±8vs. 136±11/77±9mm H g,P<.01) accompanied with increasing drug adherence. After lowering BP by fixed-dose combinations, the costs for medications decreased by 31 % over the 3 months., 本文 / Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, 6p}, school = {三重大学}, title = {Improving Drug Adherence Using Fixed Combinations Caused Beneficial Treatment Outcomes and Decreased Health-Care Costs in Patients with Hypertension}, year = {2016}, yomi = {クマガイ, ナオト} }