@techreport{oai:mie-u.repo.nii.ac.jp:00011749, author = {鈴木, 秀謙 and Suzuki, Hidenori and 阪井田, 博司 and Sakaida, Hiroshi and 松島, 聡 and Matsushima, Satoshi}, month = {May}, note = {application/pdf, 仮想脳動脈瘤モデルを用いて、まず、複雑な三次元血流の定量化を可能とする新しいパラメーターとして、時間依存性のゆらぎなどを示す複数のパラメーターを開発した。このパラメーターの脳動脈瘤破裂や増大との関連は、三重県脳動脈瘤ネットワークを介し構築した脳動脈瘤データベースに登録された未破裂脳動脈瘤と破裂脳動脈瘤の数値流体力学的特徴を比較検討することで検証した。これらの成果は多くの国内外の学会や国際誌で公表した。, Using simulated cerebral aneurysm model with blebs based on patient-specific geometry, we developed new parameters on computational fluid dynamics (CFD) that quantify 3-dimensional disturbed blood flow in the aneurysm dome. CFD analysis, a simulation process using patient-specific geometry, is a promising tool to predict the natural course of cerebral aneurysms. However, the growing number of proposed parameters remain inconsistent and confusing at least partly by inconsistent parameter definitions, flawed experimental design, or variability in assumptions and compromises adapted in CFD simulations. To confirm whether the findings are a cause, result, or mere epiphenomenon of an aneurysm behavior, a large-scale prospective cohort study of unruptured aneurysms is performing to reveal the hemodynamics of unruptured aneurysms that eventually rupture and those that do not, taking account of many factors, including physiological and humoral parameters that may affect the results., 2014年度~2015年度科学研究費補助金(挑戦的萌芽研究)研究成果報告書, 26670641}, title = {数値流体力学解析を用いた未破裂脳動脈瘤の破裂予測に関する研究}, year = {2016}, yomi = {スズキ, ヒデノリ and サカイダ, ヒロシ and マツシマ, サトシ} }