@techreport{oai:mie-u.repo.nii.ac.jp:00012436, author = {中村, 知樹 and NAKAMURA, Tomoki}, month = {May}, note = {application/pdf, 軟部腫瘍において予後や診断に関連を示したものは血清IL-6であった.IL-17は,良性および悪性で感度よりも上昇している検体はなかった.またヘプシジンなども正常であった.IL-6は悪性軟部腫瘍で有意に上昇しており、Logistic 回帰分析ではIL-6値の上昇は悪性であるOdd比が1.17(p=0.004)であり悪性の診断に有意なマーカーであった.また悪性軟部腫瘍患者59例における血清IL-6は単変量でHazard Risk(95%信頼区間)1.005 (1.002-1.008),多変量解析でもHR(95%CI)1.003 (1.000-1.006)で有意に生命予後に関連していた., We measured several kind of cytokines. Interleukin(IL)-6 was related to diagnosis in 99 patients with soft tissue mass. But, other cytokines including IL-17 were not elevated using ELISA technique. C-reactive protein (CRP) was strong co-relation with IL-6. IL-6 was useful in differentiation between benign and malignant tumors. Furthermore, we analyzed prognostic variables including IL-6 in 59 patients with soft-tissue sarcoma. IL-6 was prognostic factor for survival and event-free survival in multivariate analysis. We conclude that IL-6 may be a useful marker for diagnosis of soft tissue mass and prognostic factors for survival in soft-tissue sarcoma. Now, we analyze the relationship between micro RNA and soft tissue sarcoma., 2015年度~2016年度科学研究費補助金(若手研究(B))研究成果報告書, 15K18429}, title = {炎症性サイトカインとmicroRNAは軟部腫瘍の診断・予後因子となりうるか?}, year = {2017} }