{"created":"2023-06-19T11:43:03.177074+00:00","id":12436,"links":{},"metadata":{"_buckets":{"deposit":"01b0ce27-33e8-4500-b687-8ef3ceb02249"},"_deposit":{"created_by":15,"id":"12436","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"12436"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:00012436","sets":["631:636:1692684729425"]},"author_link":[],"item_8_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-05-22","bibliographicIssueDateType":"Issued"}}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"軟部腫瘍において予後や診断に関連を示したものは血清IL-6であった．IL-17は，良性および悪性で感度よりも上昇している検体はなかった．またヘプシジンなども正常であった．IL-6は悪性軟部腫瘍で有意に上昇しており、Logistic 回帰分析ではIL-6値の上昇は悪性であるOdd比が1.17(p=0.004)であり悪性の診断に有意なマーカーであった．また悪性軟部腫瘍患者59例における血清IL-6は単変量でHazard Risk(95%信頼区間)1.005 (1.002-1.008)，多変量解析でもHR(95%CI)1.003 (1.000-1.006)で有意に生命予後に関連していた． ","subitem_description_type":"Abstract"},{"subitem_description":"We measured several kind of cytokines. Interleukin(IL)-6 was related to diagnosis in 99 patients with soft tissue mass. But, other cytokines including IL-17 were not elevated using ELISA technique. C-reactive protein (CRP) was strong co-relation with IL-6. IL-6 was useful in differentiation between benign and malignant tumors. Furthermore, we analyzed prognostic variables including IL-6 in 59 patients with soft-tissue sarcoma. IL-6 was prognostic factor for survival and event-free survival in multivariate analysis. We conclude that IL-6 may be a useful marker for diagnosis of soft tissue mass and prognostic factors for survival in soft-tissue sarcoma. Now, we analyze the relationship between micro RNA and soft tissue sarcoma.","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"2015年度～2016年度科学研究費補助金(若手研究(B))研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"15K18429","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_31":{"attribute_name":"出版者（ヨミ）","attribute_value_mlt":[{"subitem_text_value":"ミエダイガク"}]},"item_8_text_65":{"attribute_name":"資源タイプ（三重大）","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中村, 知樹","creatorNameLang":"ja"},{"creatorName":"NAKAMURA, Tomoki","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-05-08"}],"displaytype":"detail","filename":"2018RP0054.pdf","filesize":[{"value":"163.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"2018RP0054","url":"https://mie-u.repo.nii.ac.jp/record/12436/files/2018RP0054.pdf"},"version_id":"0c91fd5b-e538-45e2-a80d-2cf104569d64"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"サイトカイン","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"炎症性サイトカインとmicroRNAは軟部腫瘍の診断・予後因子となりうるか？","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"炎症性サイトカインとmicroRNAは軟部腫瘍の診断・予後因子となりうるか？","subitem_title_language":"ja"},{"subitem_title":"Diagnostic and prognostic analysis for soft tissue tumor using inflammatory cytokine and micro RNA","subitem_title_language":"en"}]},"item_type_id":"8","owner":"15","path":["1692684729425"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-05-08"},"publish_date":"2019-05-08","publish_status":"0","recid":"12436","relation_version_is_last":true,"title":["炎症性サイトカインとmicroRNAは軟部腫瘍の診断・予後因子となりうるか？"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-11-14T00:10:18.978026+00:00"}