{"created":"2023-06-19T11:43:38.931870+00:00","id":13270,"links":{},"metadata":{"_buckets":{"deposit":"dabef648-d799-4f0b-b3df-71bfb5f35d8c"},"_deposit":{"created_by":15,"id":"13270","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"13270"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:00013270","sets":["334:627:1692670441288"]},"author_link":[],"item_8_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-05-30","bibliographicIssueDateType":"Issued"}}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"膠原病患者で肺高血圧境界領域からの早期治療介入が病勢の進行に与える効果や安全性を明らかにすることを目的に行った。境界型患者37例を対象に、右心カテーテル留置下運動負荷で平均肺動脈圧が30mmHg以上に上昇した31例を早期薬物治療介入群(E群)と非介入群（N群）に割り振り、1年ごとに同様の検査で両群間での血行動態各指標の違いを検討した。最大運動負荷時の平均肺動脈圧はE群で低下傾向に対しN群では上昇傾向を認め、運動時平均肺動脈圧の増加量やそれを心拍出量の増加量で除した割合はN群で有意に上昇していた。運動誘発性肺高血圧症に対する早期薬物治療介入は病勢進行抑制に安全かつ効果的であることが示唆された。","subitem_description_type":"Abstract"},{"subitem_description":"To eluciate the efficacy and safety the eraly pharmacological intervention for the borderline pulmonary arterial hypertension associated with connective tissue disease, we examined the hemodynamic parameters in pre- and follow-up period under exercise with right heart catheterization between treatment group and non-treatment group. Progression of abnormal response in exercise was observed in non-treatment group but not in treatment group. In conclusion, early pharmacological intervention might be safe and effective for patients with borderline pulmonary arterial hypertension to prevent pulmonary vascular remodeling.","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"2014年度～2017年度科学研究費補助金(基盤研究(C))研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"26461107","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_31":{"attribute_name":"出版者（ヨミ）","attribute_value_mlt":[{"subitem_text_value":"ミエダイガク"}]},"item_8_text_65":{"attribute_name":"資源タイプ（三重大）","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"山田, 典一","creatorNameLang":"ja"},{"creatorName":"ヤマダ, ノリカズ","creatorNameLang":"ja-Kana"},{"creatorName":"YAMADA, Norikazu","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-01-21"}],"displaytype":"detail","filename":"2019RP0040.pdf","filesize":[{"value":"183.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"2019RP0040","url":"https://mie-u.repo.nii.ac.jp/record/13270/files/2019RP0040.pdf"},"version_id":"553400a5-3659-45d6-ab41-025d7541a7e3"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"肺高血圧症","subitem_subject_scheme":"Other"},{"subitem_subject":"早期治療介入","subitem_subject_scheme":"Other"},{"subitem_subject":"運動負荷","subitem_subject_scheme":"Other"},{"subitem_subject":"薬物治療","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"境界型肺高血圧症における予後規定因子の同定と早期治療効果に関する検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"境界型肺高血圧症における予後規定因子の同定と早期治療効果に関する検討","subitem_title_language":"ja"},{"subitem_title":"Evaluation of prognostic factors and efficacy of early treatment for borderline pulmonary arterial hypertension","subitem_title_language":"en"}]},"item_type_id":"8","owner":"15","path":["1692670441288"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-01-21"},"publish_date":"2020-01-21","publish_status":"0","recid":"13270","relation_version_is_last":true,"title":["境界型肺高血圧症における予後規定因子の同定と早期治療効果に関する検討"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-11-09T02:01:38.869909+00:00"}