{"created":"2023-06-19T11:44:28.490355+00:00","id":14409,"links":{},"metadata":{"_buckets":{"deposit":"e0e20487-4b09-43ef-b6e1-351328fe99d1"},"_deposit":{"created_by":16,"id":"14409","owners":[16],"pid":{"revision_id":0,"type":"depid","value":"14409"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:00014409","sets":["334:608:618:620"]},"author_link":[],"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-03-25","bibliographicIssueDateType":"Issued"}}]},"item_7_date_granted_59":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2014-03-25"}]},"item_7_degree_grantor_57":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"三重大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"14101","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_7_degree_name_56":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士(医学)"}]},"item_7_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Thrombophilia is frequently associated with venous thromboembolism (VTE) including cerebral venous sinus thrombosis (CVST). The possibility of thrombophilia was examined in 12 patients with CSVT diagnosed in the past 9 years. Thrombophilia due to abnormalities in antithrombin(AT), protein C (PC), or protein S (PS) or antiphospholipid syndrome (APS) was evaluated. Nine patients with abnormally decreased AT, PC or PS and one patient with APS were examined. Of the nine patients examined by a gene analysis of AT, PC, or PS, one had a congenital AT deficiency, one had a congenital PC deficiency, and two had congenital PS deficiencies including a novel mutant(Gly189Ala). AT, PC and PS levels were all decreased in one patient, PS level was decreased in three patients, and AT level was decreased in one patient at the onset of CVST, but these concentrations improved after treatment. CVST is frequently associated with thrombophilia and a transient decrease in AT, PC or PS may be a causal factor.","subitem_description_type":"Abstract"}]},"item_7_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"本文/Central Laboratory, Mie University Graduate School of Medicine, Tsu, Japan","subitem_description_type":"Other"},{"subitem_description":"6p","subitem_description_type":"Other"}]},"item_7_dissertation_number_60":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲医学第1652号"}]},"item_7_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_7_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1007/s12185-012-1006-0","subitem_relation_type_select":"DOI"}}]},"item_7_text_31":{"attribute_name":"出版者（ヨミ）","attribute_value_mlt":[{"subitem_text_value":"ミエダイガク"}]},"item_7_text_63":{"attribute_name":"ノート","attribute_value_mlt":[{"subitem_text_value":"International Journal of Hematology(2012) 95:257–262に掲載"}]},"item_7_text_65":{"attribute_name":"資源タイプ（三重大）","attribute_value_mlt":[{"subitem_text_value":"Doctoral Dissertation / 博士論文"}]},"item_7_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ikejiri, Makoto","creatorNameLang":"en"},{"creatorName":"イケジリ, マコト","creatorNameLang":"ja-Kana"},{"creatorName":"池尻, 誠","creatorNameLang":"ja"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-12-09"}],"displaytype":"detail","filename":"2013DM018.pdf","filesize":[{"value":"246.3 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"2013DM018","objectType":"fulltext","url":"https://mie-u.repo.nii.ac.jp/record/14409/files/2013DM018.pdf"},"version_id":"9d8aaf8a-26d9-4eb5-9350-16aad6d33313"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Cerebral venous sinus thrombosis (CVST)","subitem_subject_scheme":"Other"},{"subitem_subject":"Thrombophilia","subitem_subject_scheme":"Other"},{"subitem_subject":"Antithrombin","subitem_subject_scheme":"Other"},{"subitem_subject":"Protein C","subitem_subject_scheme":"Other"},{"subitem_subject":"Protein S","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Frequent association of thrombophilia in cerebral venous sinus thrombosis","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Frequent association of thrombophilia in cerebral venous sinus thrombosis","subitem_title_language":"en"}]},"item_type_id":"7","owner":"16","path":["620"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-12-09"},"publish_date":"2021-12-09","publish_status":"0","recid":"14409","relation_version_is_last":true,"title":["Frequent association of thrombophilia in cerebral venous sinus thrombosis"],"weko_creator_id":"16","weko_shared_id":-1},"updated":"2023-11-08T05:55:03.502790+00:00"}