{"created":"2023-06-19T11:44:32.665405+00:00","id":14500,"links":{},"metadata":{"_buckets":{"deposit":"fc529bfa-f2f6-45a0-a7c9-0fccb981565a"},"_deposit":{"created_by":15,"id":"14500","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"14500"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:00014500","sets":["334:627:1692670486782"]},"author_link":[],"item_8_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-05-18","bibliographicIssueDateType":"Issued"}}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"胃癌における好中球浸潤の臨床的意義や、全身循環中の好中球として、NETosisに着目し、その定量化を図り、その臨床的意義を解析した結果、TEN上昇、NETs高値はともに予後不良となることがわかり、予後マーカーとなるのみならず、癌進展において深いかかわりを持つ可能性が考慮された。また本研究に付随して解析したL1CAM高発現は臨床的に有用な予後予測マーカーとなるほか、in vitro/in vivo 研究の結果、治療標的となりうる可能性を報告した。","subitem_description_type":"Abstract"},{"subitem_description":"  The aim of this study was to clarify the clinically relevance of tumor-associated neutrophils and ciculating NETosis in gastric cancer patients. Our study clealy revealed that elevetaed TANs or NETs were significantly associated with poor survival in gastric cancer patients. Furthermore, gene expression analysis demonstrated that increased L1CAM expression was deeply involved in metastatic process and poor prognosis in gastric cancer patients.","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"2017年度～2019年度科学研究費補助金(基盤研究(C))研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"17K10584","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_31":{"attribute_name":"出版者（ヨミ）","attribute_value_mlt":[{"subitem_text_value":"ミエダイガク"}]},"item_8_text_65":{"attribute_name":"資源タイプ（三重大）","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"毛利, 靖彦","creatorNameLang":"ja"},{"creatorName":"モウリ, ヤスヒコ","creatorNameLang":"ja-Kana"},{"creatorName":"Mohri, Yasuhiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"問山, 裕二","creatorNameLang":"ja"},{"creatorName":"トイヤマ, ユウジ","creatorNameLang":"ja-Kana"},{"creatorName":"Toiyama, Yuji","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"大井, 正貴","creatorNameLang":"ja"},{"creatorName":"オオイ, マサキ","creatorNameLang":"ja-Kana"},{"creatorName":"Ohi, Masaki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"楠, 正人","creatorNameLang":"ja"},{"creatorName":"クスノキ, マサト","creatorNameLang":"ja-Kana"},{"creatorName":"Kusunoki, Masato","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-01-19"}],"displaytype":"detail","filename":"2021RP0034.pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"2021RP0034","url":"https://mie-u.repo.nii.ac.jp/record/14500/files/2021RP0034.pdf"},"version_id":"7973e92f-c012-454c-8de0-00ba52b85a75"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"胃癌","subitem_subject_scheme":"Other"},{"subitem_subject":"好中球","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"腫瘍関連好中球に着目した胃癌リンパ節転移機構の解明と新規治療法の開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"腫瘍関連好中球に着目した胃癌リンパ節転移機構の解明と新規治療法の開発","subitem_title_language":"ja"},{"subitem_title":"Elucidation for pivotal role of tumor associated neutrophis in gastric cancer.","subitem_title_language":"en"}]},"item_type_id":"8","owner":"15","path":["1692670486782"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-01-19"},"publish_date":"2022-01-19","publish_status":"0","recid":"14500","relation_version_is_last":true,"title":["腫瘍関連好中球に着目した胃癌リンパ節転移機構の解明と新規治療法の開発"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-11-09T05:32:23.479187+00:00"}