{"created":"2023-06-19T11:44:34.169307+00:00","id":14534,"links":{},"metadata":{"_buckets":{"deposit":"a73dd782-edf3-4df0-bb5c-249549b95392"},"_deposit":{"created_by":15,"id":"14534","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"14534"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:00014534","sets":["631:636:1692684799396"]},"author_link":["47712","47713","47714","47715"],"item_8_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-05-18","bibliographicIssueDateType":"Issued"}}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"潰瘍性大腸炎患者において直腸粘膜のDNAメチル化レベル、DMRsパネルが潰瘍性大腸炎患者関連大腸癌を高率に同定でき、有用なpredictive markerとなり得る可能性が示唆された。\n大腸癌組織中のFusobacterium発現とMSI-H大腸癌との関連性が示され、MSI-H大腸癌の発癌と大腸におけるFusobacterium発現が関与する可能性が示唆された。また、口腔内細菌叢の解析には進めなかった。","subitem_description_type":"Abstract"},{"subitem_description":" Specific miRNAs to be methylated and DMRs in rectal mucosal in patients with UC could be used to identify patients with UC at greatest risk for developing UC-CRC. Fusobacterium infection was detected in CRC tissues. Furthermore, Fusobacterium infection was significantly associated with MSI-H compared to non-MSI-H. Unfortunately, it is difficult to detect the oral microbiota and we could not process comprehensive analysis of oral microbiota.","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"2017年度～2019年度科学研究費補助金(基盤研究(C))研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"17K10629","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_31":{"attribute_name":"出版者（ヨミ）","attribute_value_mlt":[{"subitem_text_value":"ミエダイガク"}]},"item_8_text_65":{"attribute_name":"資源タイプ（三重大）","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"近藤, 哲","creatorNameLang":"ja"},{"creatorName":"コンドウ, サトル","creatorNameLang":"ja-Kana"},{"creatorName":"Kondo, Satoru","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"問山, 裕二","creatorNameLang":"ja"},{"creatorName":"トイヤマ, ユウジ","creatorNameLang":"ja-Kana"},{"creatorName":"Toiyama, Yuji","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"奥川, 喜永","creatorNameLang":"ja"},{"creatorName":"オクガワ, ヨシナガ","creatorNameLang":"ja-Kana"},{"creatorName":"Okugawa, Yoshinaga","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"楠, 正人","creatorNameLang":"ja"},{"creatorName":"クスノキ, マサト","creatorNameLang":"ja-Kana"},{"creatorName":"Kusunoki, Masato","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-01-24"}],"displaytype":"detail","filename":"2021RP0068.pdf","filesize":[{"value":"788.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"2021RP0068","url":"https://mie-u.repo.nii.ac.jp/record/14534/files/2021RP0068.pdf"},"version_id":"5c9b5c31-b411-4d41-9f5b-d68302b11cc0"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"大腸癌","subitem_subject_scheme":"Other"},{"subitem_subject":"潰瘍性大腸炎","subitem_subject_scheme":"Other"},{"subitem_subject":"腸内細菌","subitem_subject_scheme":"Other"},{"subitem_subject":"マイクロサテライト不安定性","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"網羅的口腔内細菌叢の解析から検証する大腸癌発癌の機序","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"網羅的口腔内細菌叢の解析から検証する大腸癌発癌の機序","subitem_title_language":"ja"},{"subitem_title":"Association carcinogenesis with oral microbiota in colorectal cancer","subitem_title_language":"en"}]},"item_type_id":"8","owner":"15","path":["1692684799396"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-01-24"},"publish_date":"2022-01-24","publish_status":"0","recid":"14534","relation_version_is_last":true,"title":["網羅的口腔内細菌叢の解析から検証する大腸癌発癌の機序"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-11-14T02:12:15.255697+00:00"}