{"created":"2023-06-19T11:45:03.746066+00:00","id":15271,"links":{},"metadata":{"_buckets":{"deposit":"f5a89e5f-043f-4f98-9db3-cef06fdb5c58"},"_deposit":{"created_by":15,"id":"15271","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"15271"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:00015271","sets":["334:627:1692670514969"]},"author_link":[],"item_8_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-06-09","bibliographicIssueDateType":"Issued"}}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"胃癌腹膜播種モデルマウスにおける温熱化学療法のアブスコパル効果を直接的に解析することは手技の確立に難渋し、困難であった。\n細胞接着因子であるL１CAMの胃癌細胞における発現が腹膜播種に関与している可能性を示唆した。さらに、胃癌組織中のPD-L1発現も腹膜播種転移に相関することを同定した。宿主因子に着目し、癌免疫反応マーカーであるCLRが有意に栄養・予後と相関し、胃癌患者においてより高リスク群を抽出できる可能性を示唆された。","subitem_description_type":"Abstract"},{"subitem_description":"It was difficult to elucidate for abscopal effect with intra-abdominal hyperthermia chemotherapy, because we could not make the mouse model with gastric cancer peritoneal metastases.\nHigh L1CAM expression was significantly associated with peritoneal metastasis. Gastric cancer tissue PD-L1 expression was significantly higher in the GC patients with and peritoneal metastasis.\nAdditionally, CLR size correlated with patient nutritional status and prognosis and may be helpful in identifying high-risk populations of GC patients.","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"2018年度～2020年度科学研究費補助金(基盤研究(C))研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"18K08592","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_31":{"attribute_name":"出版者（ヨミ）","attribute_value_mlt":[{"subitem_text_value":"ミエダイガク"}]},"item_8_text_65":{"attribute_name":"資源タイプ（三重大）","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"三木, 誓雄","creatorNameLang":"ja"},{"creatorName":"ミキ, チカオ","creatorNameLang":"ja-Kana"},{"creatorName":"Miki, Chikao","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"問山, 裕二","creatorNameLang":"ja"},{"creatorName":"トイヤマ, ユウジ","creatorNameLang":"ja-Kana"},{"creatorName":"Toiyama, Yuji","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"奥川, 喜永","creatorNameLang":"ja"},{"creatorName":"オクガワ, ヨシナガ","creatorNameLang":"ja-Kana"},{"creatorName":"Okugawa, Hiroyuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"藤川, 裕之","creatorNameLang":"ja"},{"creatorName":"フジカワ, ヒロユキ","creatorNameLang":"ja-Kana"},{"creatorName":"Fujikawa, Hiroyuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"安田, 裕美","creatorNameLang":"ja"},{"creatorName":"ヤスダ, ヒロミ","creatorNameLang":"ja-Kana"},{"creatorName":"Yasuda, Hiromi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"楠, 正人","creatorNameLang":"ja"},{"creatorName":"クスノキ, マサト","creatorNameLang":"ja-Kana"},{"creatorName":"Kusunoki, Masato","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-11-24"}],"displaytype":"detail","filename":"2022RP0032.pdf","filesize":[{"value":"234.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"2022RP0032","url":"https://mie-u.repo.nii.ac.jp/record/15271/files/2022RP0032.pdf"},"version_id":"92e9bdef-524b-4554-9db2-ab5a083b3710"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"胃癌","subitem_subject_scheme":"Other"},{"subitem_subject":"アブスコパル効果","subitem_subject_scheme":"Other"},{"subitem_subject":"腹膜播種","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"アブスコパル効果の概念から考案した腹腔内温熱化学療法の有効性の検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"アブスコパル効果の概念から考案した腹腔内温熱化学療法の有効性の検討","subitem_title_language":"ja"},{"subitem_title":"Consideration of effectiveness of intra-abdominal hyperthermia chemotherapy devised from abscopal effect","subitem_title_language":"en"}]},"item_type_id":"8","owner":"15","path":["1692670514969"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-11-24"},"publish_date":"2022-11-24","publish_status":"0","recid":"15271","relation_version_is_last":true,"title":["アブスコパル効果の概念から考案した腹腔内温熱化学療法の有効性の検討"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-11-10T02:02:31.086889+00:00"}