{"created":"2023-12-12T05:48:40.014515+00:00","id":2000181,"links":{},"metadata":{"_buckets":{"deposit":"f4762e2e-14c6-422f-a3ad-3f42c0a1105b"},"_deposit":{"created_by":15,"id":"2000181","owner":"15","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"2000181"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:02000181","sets":["334:627:1701929182893"]},"author_link":[],"control_number":"2000181","item_8_biblio_info_6":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-05-19","bibliographicIssueDateType":"Issued"}}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"本研究ではマラリア原虫の各転写因子の機能、結合配列、標的遺伝子等の解析を実施した。この成果により,１つの転写因子が遺伝子を直接かつ包括的に制御し各ステージの遺伝子発現レパートリーを決定するというマラリア原虫のユニークな転写制御機構を実証することに成功した。また、マラリア原虫のライフサイクルをターゲトームの連鎖として捉え、各ステージ間の遺伝子発現のダイナミックな連関に光を当てることに成功した","subitem_description_type":"Abstract"},{"subitem_description":"In this study, we analyzed the function of each Plasmodium transcription factor, identified its binding sequences, and determined target genes. Our results demonstrated the unique transcriptional regulation mechanism of Plasmodium parasites, in which a stage-specific transcription factor directly and comprehensively regulates genes and determines the gene expression repertoire at each stage. We have also revealed the dynamic linkage of gene expression through the lifecycle by viewing it as a chain of targetomes.","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"2017年度～2019年度科学研究費補助金(基盤研究(A))研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"17H01542","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_31":{"attribute_name":"出版者（ヨミ）","attribute_value_mlt":[{"subitem_text_value":"ミエダイガク"}]},"item_8_text_65":{"attribute_name":"item_8_text_65","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"油田, 正夫","creatorNameLang":"ja"},{"creatorName":"yuda, masao","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-12-12"}],"filename":"2023RP0017.pdf","filesize":[{"value":"430 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://mie-u.repo.nii.ac.jp/record/2000181/files/2023RP0017.pdf"},"version_id":"8fcf007a-d6fe-46e5-a024-ee74c50297e2"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"マラリア","subitem_subject_scheme":"Other"},{"subitem_subject":"転写因子","subitem_subject_scheme":"Other"},{"subitem_subject":"ターゲトーム","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"item_resource_type","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"ターゲト－ムによるマラリア原虫ライフサイクルの統一的理解","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ターゲト－ムによるマラリア原虫ライフサイクルの統一的理解","subitem_title_language":"ja"},{"subitem_title":"Unified Understanding of the Plasmodium Life Cycle by Targetome Analysis","subitem_title_language":"en"}]},"item_type_id":"8","owner":"15","path":["1701929182893"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-12-12"},"publish_date":"2023-12-12","publish_status":"0","recid":"2000181","relation_version_is_last":true,"title":["ターゲト－ムによるマラリア原虫ライフサイクルの統一的理解"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2024-09-20T01:06:41.233544+00:00"}