{"created":"2023-12-15T00:58:09.040045+00:00","id":2000209,"links":{},"metadata":{"_buckets":{"deposit":"45d765ad-c7cb-411c-acec-b36ccc9be5d5"},"_deposit":{"created_by":15,"id":"2000209","owner":"15","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"2000209"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:02000209","sets":["631:636:1701929233389"]},"author_link":[],"control_number":"2000209","item_8_biblio_info_6":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-05-25","bibliographicIssueDateType":"Issued"}}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"我々はヒルシュスプルング病患者において、二光子レーザー顕微鏡をもちいた腸管神経システムの観察可能性を研究した。外科的摘出した患者の大腸検体をクルクミン色素で散布染色し、腸管の外側から顕微鏡で観察した。人の大腸壁内の腸管神経叢や神経ネットワークがクリアに描出され、口側から肛門側への、腸管神経細胞の減少だけでなく、一つの腸管神経叢から分岐する神経束数の減少もとらえることができた。","subitem_description_type":"Abstract"},{"subitem_description":"We investigated the possibility of observing the enteric nervous system (ENS) using two-photon laser scanning microscopy (TPLSM) in allied disorder of Hirschsprung disease patient. The colonic tissue (between transverse and rectum) just after operational resection was quickly dyed by curcumin. After 5 minutes’ curcumin vital staining, intestinal wall scan from serosal side was performed by TPLSM without opening the intestinal wall.\nVisualization of the myenteric plexus without opening the intestinal wall was performed successfully in human colonic tissue. At oral edge of the resected specimen, the size of myenteric plexus and its neural network were normal. On the other hand, from oral edge to anal edge, the myenteric plexus size was shrunk gradually and the neural network were decreased by degrees. Furthermore, at anal edge of the observational area, there was only hypoplastic shrunk myenteric plexus without neural network to other plexus.","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"2019年度~2021年度科学研究費補助金(基盤研究(C))研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"19K09091","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_31":{"attribute_name":"出版者(ヨミ)","attribute_value_mlt":[{"subitem_text_value":"ミエダイガク"}]},"item_8_text_65":{"attribute_name":"item_8_text_65","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"内田, 恵一","creatorNameLang":"ja"},{"creatorName":"Uchida, Keiichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"小池, 勇樹","creatorNameLang":"ja"},{"creatorName":"Koike, Yuhki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"井上, 幹大","creatorNameLang":"ja"},{"creatorName":"Inoue, Mikihiro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"松下, 航平","creatorNameLang":"ja"},{"creatorName":"Matsushita, Kohei","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"溝口, 明","creatorNameLang":"ja"},{"creatorName":"Mizoguchi, Akira","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"楠, 正人","creatorNameLang":"ja"},{"creatorName":"Kusunoki, Masato","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-12-15"}],"filename":"2023RP0047.pdf","filesize":[{"value":"490 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://mie-u.repo.nii.ac.jp/record/2000209/files/2023RP0047.pdf"},"version_id":"bfa49a7c-41cf-4d7c-820d-4551408ea431"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ヒルシュスプルング病","subitem_subject_scheme":"Other"},{"subitem_subject":"二光子レーザー顕微鏡","subitem_subject_scheme":"Other"},{"subitem_subject":"腸管神経叢","subitem_subject_scheme":"Other"},{"subitem_subject":"外科手術","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"item_resource_type","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"ヒルシュスプルング病における腸管壁内神経節細胞局在の二光子レーザー顕微鏡観察研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ヒルシュスプルング病における腸管壁内神経節細胞局在の二光子レーザー顕微鏡観察研究","subitem_title_language":"ja"},{"subitem_title":"Analysis for the intestinal enteric nervous system of Hirschsprung disease patients by the novel intravital fluorescent observation method","subitem_title_language":"en"}]},"item_type_id":"8","owner":"15","path":["1701929233389"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-12-15"},"publish_date":"2023-12-15","publish_status":"0","recid":"2000209","relation_version_is_last":true,"title":["ヒルシュスプルング病における腸管壁内神経節細胞局在の二光子レーザー顕微鏡観察研究"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2024-09-24T02:16:02.637988+00:00"}