{"created":"2023-12-15T04:18:30.872199+00:00","id":2000215,"links":{},"metadata":{"_buckets":{"deposit":"4e044506-3cf1-445e-8e32-a5c3254be506"},"_deposit":{"created_by":15,"id":"2000215","owner":"15","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"2000215"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:02000215","sets":["631:636:1701929233389"]},"author_link":[],"control_number":"2000215","item_8_biblio_info_6":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-06-20","bibliographicIssueDateType":"Issued"}}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"本研究結果は、食事成因の違いによって、脂肪肝の虚血再灌流傷害（肝IRI）に違いが生じることを示唆した。フルクトース食によってもたらせられた脂肪肝は、脂肪食によってもたらせられたものとくらべ、より高度な肝IRIを示した。　\nまた、各脂肪肝によって障害前からE-cadherinの発現に違いが認められ、発現が低い脂肪肝ほど、再灌流後の発現も低くなり、肝障害度も強く認められた。この結果はE-cadherinのIRIにおける細胞保護効果を示唆するものと考えられた。","subitem_description_type":"Abstract"},{"subitem_description":"The results of this study suggested that different dietary factors caused differences in ischemia-reperfusion injury (IRI) in fatty liver. Fatty liver caused by the fructose diet showed a severe liver IRI than that caused by the fat diet.　\nThe expression of E-cadherin was different depending on each etiology before IRI. The lower the expression of E-caherin, the stronger the degree of liver damage was observed. This result suggested the cytoprotective effect of E-cadherin on hepatic IRI.","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"2019年度～2021年度科学研究費補助金(若手研究)研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"19K18023","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_31":{"attribute_name":"出版者（ヨミ）","attribute_value_mlt":[{"subitem_text_value":"ミエダイガク"}]},"item_8_text_65":{"attribute_name":"item_8_text_65","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"藤井, 武宏","creatorNameLang":"ja"},{"creatorName":"FUJII, TAKEHIRO","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-12-15"}],"filename":"2023RP0053.pdf","filesize":[{"value":"418 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://mie-u.repo.nii.ac.jp/record/2000215/files/2023RP0053.pdf"},"version_id":"317fa59e-0f9e-44d3-bf79-16697f9f26a9"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"虚血再灌流傷害","subitem_subject_scheme":"Other"},{"subitem_subject":"脂肪肝","subitem_subject_scheme":"Other"},{"subitem_subject":"細胞間接着分子","subitem_subject_scheme":"Other"},{"subitem_subject":"E-cadherin","subitem_subject_scheme":"Other"},{"subitem_subject":"アポトーシス","subitem_subject_scheme":"Other"},{"subitem_subject":"肝移植","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"item_resource_type","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"細胞間接着分子発現抑制を介した脂肪肝虚血再灌流障害機序の解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"細胞間接着分子発現抑制を介した脂肪肝虚血再灌流障害機序の解明","subitem_title_language":"ja"},{"subitem_title":"Mechanism of ischemia-reperfusion injury in fatty liver caused by suppression of intercellular adhesion molecule expression","subitem_title_language":"en"}]},"item_type_id":"8","owner":"15","path":["1701929233389"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-12-15"},"publish_date":"2023-12-15","publish_status":"0","recid":"2000215","relation_version_is_last":true,"title":["細胞間接着分子発現抑制を介した脂肪肝虚血再灌流障害機序の解明"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2024-09-24T02:39:19.945056+00:00"}