{"created":"2023-12-19T00:47:34.110314+00:00","id":2000226,"links":{},"metadata":{"_buckets":{"deposit":"a95a4d45-f978-4d75-a01c-d60f5b74346f"},"_deposit":{"created_by":15,"id":"2000226","owner":"15","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"2000226"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:02000226","sets":["631:636:1701929233389"]},"author_link":[],"control_number":"2000226","item_8_biblio_info_6":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-05-16","bibliographicIssueDateType":"Issued"}}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"MRI を用いた血流と拡散の研究は、脳腫瘍で活発に行われ臨床的にも有用性が確立しているが、頭頸部腫瘍においては十分に検討がされていない。本研究の目的は、3 テスラMRI を使い、頭頸部腫瘍における血流と拡散の情報を非侵襲的に取得する新たな撮影法とそれらのデータを定量評価するための解析ソフトウェアを開発することである。ターボスピンエコー法を用いたarterial spin labelingという血流撮像法と拡散強調画像で頭頚部腫瘍の定量的評価法の確立を試みた。血流量と拡散の情報を解析するソフトウェアを使うことで頭頚部腫瘍の診断で良悪性の鑑別が可能となり、腫瘍の質的診断に有用であることを証明した。","subitem_description_type":"Abstract"},{"subitem_description":"Pseudocont inuous arterial spin labeling (pCASL) imaging enables noninvasive quantification of tumor blood flow in the head and neck. The purpose of this study was to compare echo-planar (EP) and turbo spin-echo (TSE) sequences of pCASL, to demonstrate the clinical applications and usefulness of this method in the diagnosis of particular diseases via both tumor blood flow (TBF) quantification and the apparent diffusion coefficient (ADC) obtained by diffusion-weighted imaging (DWI), and to demonstrate changes in TBF after chemoradiation treatments.\nTSE pCASL showed less image torsion and higher lesion conspicuity than EP pCASL. Combination of TSE pCASL and ADC enabled to differentiate benign parotid tumors from malignant parotid tumors. TBF changes were observed in head and neck squamous cell carcinomas in response to chemoradiation at an early stage. This study showed that the combination of pCASL and ADC is a promising tool for head and neck tumors.","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"2016年度～2021年度科学研究費補助金(基盤研究(C))研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"16K10314","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_31":{"attribute_name":"出版者（ヨミ）","attribute_value_mlt":[{"subitem_text_value":"ミエダイガク"}]},"item_8_text_65":{"attribute_name":"item_8_text_65","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"海野, 真記","creatorNameLang":"ja"},{"creatorName":"Umino, Maki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"前田, 正幸","creatorNameLang":"ja"},{"creatorName":"Maeda, Masayuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"野本, 由人","creatorNameLang":"ja"},{"creatorName":"Nomoto, Yoshihito","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"中山, 良平","creatorNameLang":"ja"},{"creatorName":"Nakayama, Ryohei","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-12-19"}],"filename":"2023RP0064.pdf","filesize":[{"value":"515 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://mie-u.repo.nii.ac.jp/record/2000226/files/2023RP0064.pdf"},"version_id":"81b6621d-6c66-4ac3-85ab-106cf9a1a3d6"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"頭頚部腫瘍","subitem_subject_scheme":"Other"},{"subitem_subject":"機能的MRI撮影法","subitem_subject_scheme":"Other"},{"subitem_subject":"画像解析","subitem_subject_scheme":"Other"},{"subitem_subject":"arterial spin labeling","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"item_resource_type","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"機能的MR撮影法による頭頸部腫瘍の診断と早期治療効果判定の検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"機能的MR撮影法による頭頸部腫瘍の診断と早期治療効果判定の検討","subitem_title_language":"ja"},{"subitem_title":"Pseudo-Continuous Arterial Spin Labeling: Clinical Application and Usefulness for Head and Neck Tumors","subitem_title_language":"en"}]},"item_type_id":"8","owner":"15","path":["1701929233389"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-12-19"},"publish_date":"2023-12-19","publish_status":"0","recid":"2000226","relation_version_is_last":true,"title":["機能的MR撮影法による頭頸部腫瘍の診断と早期治療効果判定の検討"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2024-09-24T04:18:18.911532+00:00"}