{"created":"2024-10-18T00:52:35.538395+00:00","id":2000943,"links":{},"metadata":{"_buckets":{"deposit":"a189603d-4b5a-4f5e-8aca-b1bcba94a75d"},"_deposit":{"created_by":15,"id":"2000943","owner":"15","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"2000943"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:02000943","sets":["334:627:1728958044917"]},"author_link":[],"item_8_biblio_info_6":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-06-13","bibliographicIssueDateType":"Issued"}}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"本研究では、キトサンエアロゲルを腸管吻合部の補強材として生体応用することを目的として実験を実施した。作製したキトサンエアロゲルについてブタの小腸を用いて各種のin vitro物性評価試験を実施した結果、腸管の激しい蠕動運動に追従可能な高い柔軟性、強度、生体接着力と、高い腸内圧に耐久可能な耐圧性を有していることが示された。さらに、細胞毒性試験および動物実験から、キトサンエアロゲルが高い生体適合性を有していることが示されたものの、生体内における小腸への貼付安定性に課題を有することも明らかとなり、改良型エアロゲルにて検討を行っている。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"In this study, experiments were conducted to apply chitosan aerogel as a reinforcement material for intestinal anastomosis in vivo. The results of various in vitro experiments of physical property evaluation using porcine intestine showed that the chitosan aerogel has high flexibility, strength, and bioadhesiveness that can follow the intense peristalsis of the intestinal tract, and high pressure resistance that can withstand high intestinal pressure. Furthermore, the results of cytotoxicity tests and animal experiments showed that the chitosan aerogel has high biocompatibility. However, it was also found that there is a problem with the stability of its application to the intestine in vivo, so an improved aerogel is being investigated.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"2020年度～2022年度科学研究費補助金(基盤研究(C))研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"20K08979","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_31":{"attribute_name":"出版者（ヨミ）","attribute_value_mlt":[{"subitem_text_value":"ミエダイガク"}]},"item_8_text_65":{"attribute_name":"item_8_text_65","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"横田, 一樹","creatorNameLang":"ja"},{"creatorName":"YOKOTA, KAZUKI","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"内田, 広夫","creatorNameLang":"ja"},{"creatorName":"Uchida, Hiroo","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"檜, 顕成","creatorNameLang":"ja"},{"creatorName":"Hinoki, Akinari","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"城田, 千代栄","creatorNameLang":"ja"},{"creatorName":"Shirota, Chiyoe","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"武岡, 真司","creatorNameLang":"ja"},{"creatorName":"Takeoka, Shinji","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"藤枝, 俊宣","creatorNameLang":"ja"},{"creatorName":"Fujie, Toshinori","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-10-18"}],"filename":"2024RP0034.pdf","filesize":[{"value":"350 KB"}],"format":"application/pdf","url":{"label":"2024RP0034.pdf","url":"https://mie-u.repo.nii.ac.jp/record/2000943/files/2024RP0034.pdf"},"version_id":"7fd1dfc5-de6d-4ad3-887f-39368dd9e23e"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"キトサン","subitem_subject_scheme":"Other"},{"subitem_subject":"エアロゲル","subitem_subject_scheme":"Other"},{"subitem_subject":"補強材","subitem_subject_scheme":"Other"},{"subitem_subject":"腸管吻合","subitem_subject_scheme":"Other"},{"subitem_subject":"縫合不全","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"item_resource_type","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"縫合不全と術後癒着防止のための自己支持性高分子超薄膜(ナノシート)の開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"縫合不全と術後癒着防止のための自己支持性高分子超薄膜(ナノシート)の開発","subitem_title_language":"ja"},{"subitem_title":"Development of a self-supporting ultrathin polymer film (nanosheet) for preventing postoperative suture failure and adhesion","subitem_title_language":"en"}]},"item_type_id":"8","owner":"15","path":["1728958044917"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-10-18"},"publish_date":"2024-10-18","publish_status":"0","recid":"2000943","relation_version_is_last":true,"title":["縫合不全と術後癒着防止のための自己支持性高分子超薄膜(ナノシート)の開発"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2024-10-18T01:04:29.061232+00:00"}