{"created":"2024-10-18T02:15:51.567742+00:00","id":2000947,"links":{},"metadata":{"_buckets":{"deposit":"9a07e0e8-9155-4aba-82d7-29c070fdb12d"},"_deposit":{"created_by":15,"id":"2000947","owner":"15","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"2000947"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:02000947","sets":["334:627:1728958044917"]},"author_link":[],"item_8_biblio_info_6":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-05-16","bibliographicIssueDateType":"Issued"}}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"頚動脈狭窄症は脳梗塞の原因として依然、重要である。数値流体力学(CFD)は脳血管障害の病態を解析する目的で発展してきた。本研究では頚動脈狭窄症の形状不整をCFDを利用して客観的に定量化し、頚動脈狭窄症の新たな脳梗塞発症リスク評価に活用することを目的とした。即ち、三次元的に血流の構造複雑性および時間依存性ゆらぎを示す新たなパラメーターを開発し、CFD的に頚動脈狭窄症の形状不整を定量化したが、現時点では脳梗塞発症リスク評価としては不十分であった。一方、随時中性脂肪値が頚動脈狭窄症の形状不整や狭窄進行に関与する可能性が明らかとなり、心血管イベント抑制に向けた新たな治療戦略構築への応用が期待された。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"Carotid artery stenosis remains an important cause of cerebral infarction, and computational fluid dynamics (CFD) has been developed for the purpose of analyzing the pathology of cerebrovascular accidents. In this study, we objectively tried to quantify the shape irregularity of carotid artery stenosis using CFD, and to evaluate the risk of developing cerebral infarction in carotid artery stenosis. We developed new parameters that show the structural complexity and time dependent fluctuation of blood flow three-dimensionally by CFD. However, at present they were insufficient as a risk assessment for the onset of cerebral infarction. On the other hand, it became clear that non-fasting triglyceride level may be involved in the shape irregularity and stenosis progression of carotid artery stenosis, and its application to the development of new therapeutic strategies for the suppression of cardiovascular events was expected.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"2020年度～2022年度科学研究費補助金(基盤研究(C))研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"20K09346","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_31":{"attribute_name":"出版者（ヨミ）","attribute_value_mlt":[{"subitem_text_value":"ミエダイガク"}]},"item_8_text_65":{"attribute_name":"item_8_text_65","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"鈴木, 秀謙","creatorNameLang":"ja"},{"creatorName":"Suzuki, Hidenori","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-10-18"}],"filename":"2024RP0038.pdf","filesize":[{"value":"915 KB"}],"format":"application/pdf","url":{"label":"2024RP0038.pdf","url":"https://mie-u.repo.nii.ac.jp/record/2000947/files/2024RP0038.pdf"},"version_id":"62b9b38e-5937-492d-bf1b-a376bdde34e3"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"頚動脈狭窄症","subitem_subject_scheme":"Other"},{"subitem_subject":"脳梗塞","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"item_resource_type","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"頸動脈狭窄症における局所的乱流と脳梗塞発症リスクに関する研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"頸動脈狭窄症における局所的乱流と脳梗塞発症リスクに関する研究","subitem_title_language":"ja"},{"subitem_title":"Local turbulence and stroke risk in carotid artery stenosis","subitem_title_language":"en"}]},"item_type_id":"8","owner":"15","path":["1728958044917"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-10-18"},"publish_date":"2024-10-18","publish_status":"0","recid":"2000947","relation_version_is_last":true,"title":["頸動脈狭窄症における局所的乱流と脳梗塞発症リスクに関する研究"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2024-10-18T02:43:23.977575+00:00"}