{"created":"2024-10-23T02:30:19.646542+00:00","id":2000971,"links":{},"metadata":{"_buckets":{"deposit":"c59c23c4-eeb9-4d06-9de2-3e3f8359a877"},"_deposit":{"created_by":15,"id":"2000971","owner":"15","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"2000971"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:02000971","sets":["631:636:1728958087061"]},"author_link":[],"control_number":"2000971","item_8_biblio_info_6":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-05-14","bibliographicIssueDateType":"Issued"}}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Dual-energy CTによる肝ダイナミック造影CTの平衡相からヨード密度画像を生成し、ヘマトクリット及び血液の造影効果で補正した全肝の3次元的なECVマップを生成した。またECVマップから血液成分を示す高いヨード密度値の領域を、閾値を用いて除去する方法を考案した。測定された肝ECVは、高度肝線維化(F4)を高い精度で除外するのに有用であることが示された(陰性的中率91%)。さらにTc-99m GSA肝受容体SPECT定量評価は、重度肝線維化の判定に有用で、FIB-4等の他の肝機能指標と組み合わせることで、高い精度で肝線維化重症度の判定が可能であることが明らかとなった。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"Iodine density images were generated from the equilibrium phase of dual-energy dynamic contrast-enhanced CT of the liver, and three-dimensional ECV maps of the whole liver corrected with hematocrit and blood contrast effects were generated in this study. A method to remove regions of high iodine density values indicative of blood components from the ECV map was also developed using a threshold value. The measured liver ECVs were shown to be useful in excluding severe liver fibrosis (F4) with high negative predictive value 91%. Furthermore, Tc-99m GSA liver receptor SPECT quantitative evaluation, when combined with other liver function indices such as FIB-4, proved to be useful in assessing liver fibrosis.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"2020年度～2022年度科学研究費補助金(基盤研究(C))研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"20K08077","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_31":{"attribute_name":"出版者（ヨミ）","attribute_value_mlt":[{"subitem_text_value":"ミエダイガク"}]},"item_8_text_65":{"attribute_name":"item_8_text_65","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"市川, 泰崇","creatorNameLang":"ja"},{"creatorName":"Ichikawa, Yasutaka","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"中山, 良平","creatorNameLang":"ja"},{"creatorName":"Nakayama, Ryohei","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"永田, 幹紀","creatorNameLang":"ja"},{"creatorName":"Nagata, Motonori","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-10-23"}],"filename":"2024RP0061.pdf","filesize":[{"value":"555 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"2024RP0061.pdf","url":"https://mie-u.repo.nii.ac.jp/record/2000971/files/2024RP0061.pdf"},"version_id":"522ba9b6-064c-45b3-bc7d-c80eb1d6eaa1"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"肝機能","subitem_subject_scheme":"Other"},{"subitem_subject":"肝線維化","subitem_subject_scheme":"Other"},{"subitem_subject":"99mTc-GSA肝受容体SPECT","subitem_subject_scheme":"Other"},{"subitem_subject":"Dual-energy CT","subitem_subject_scheme":"Other"},{"subitem_subject":"細胞外容積分画","subitem_subject_scheme":"Other"},{"subitem_subject":"細胞内容積分画","subitem_subject_scheme":"Other"},{"subitem_subject":"肝切除術","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"item_resource_type","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"肝細胞内容積と肝細胞機能の統合的診断の開発と肝切除術前評価への応用","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"肝細胞内容積と肝細胞機能の統合的診断の開発と肝切除術前評価への応用","subitem_title_language":"ja"},{"subitem_title":"Development of integrated diagnostic method combining the assessment of hepatic intracellular volume and the assessment of hepatic cellular function for predicting liver function after hepatectomy","subitem_title_language":"en"}]},"item_type_id":"8","owner":"15","path":["1728958087061"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-10-23"},"publish_date":"2024-10-23","publish_status":"0","recid":"2000971","relation_version_is_last":true,"title":["肝細胞内容積と肝細胞機能の統合的診断の開発と肝切除術前評価への応用"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2024-10-23T02:41:48.798299+00:00"}