{"created":"2024-10-24T01:13:15.013031+00:00","id":2000984,"links":{},"metadata":{"_buckets":{"deposit":"e8d7658c-6296-42a4-898d-c126728c8f5b"},"_deposit":{"created_by":15,"id":"2000984","owner":"15","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"2000984"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:02000984","sets":["631:636:1728958087061"]},"author_link":[],"item_8_biblio_info_6":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-06-05","bibliographicIssueDateType":"Issued"}}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"pilot study として、肺癌の放射線治療患者7 例に対し、経時的に血中TNC濃度の測定を行い、放射線肺臓炎陰影が最も強くなる時期にかけて血中TNC濃度が上昇し、その後肺臓炎陰影が収束するにつれて低下するという結果を得ている。また、肺癌で照射後に手術が行われた症例（Archival tissue samples）において、切除肺の照射領域においてTNCが高発現していることを確認している。これらの結果を検証する為、マウスの肺部分照射モデルを作成し、その方法を確立した。現在、その結果を欧米のJournalに投稿中。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"In a pilot study, blood TNC levels were measured over time in seven patients treated with radiotherapy for lung cancer, and the results showed that blood TNC levels increased during the period when the radiation pneumonitis shadow was most intense, and then decreased as the neumonitis shadow subsided. In addition, we have confirmed that TNCs are highly expressed in the irradiated area of resected lungs in patients with lung cancer who underwent surgery after irradiation (archival tissue samples). To validate these results, we have established a method to create a mouse model of partial lung irradiation. The results are currently being submitted to European and American journals.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"2019年度～2022年度科学研究費補助金(基盤研究(C))研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"19K08226","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_31":{"attribute_name":"出版者（ヨミ）","attribute_value_mlt":[{"subitem_text_value":"ミエダイガク"}]},"item_8_text_65":{"attribute_name":"item_8_text_65","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"高田, 彰憲","creatorNameLang":"ja"},{"creatorName":"Takada, Akinori","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"野本, 由人","creatorNameLang":"ja"},{"creatorName":"Nomoto, Yoshihito","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"俵, 功","creatorNameLang":"ja"},{"creatorName":"Tawara, Isao","creatorNameLang":"en"}]},{"creatorAlternatives":[{"creatorAlternative":"今中, 恭子","creatorAlternativeLang":"ja"}],"creatorNames":[{"creatorName":"吉田, 恭子","creatorNameLang":"ja"},{"creatorName":"Yoshida, Kyouko","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-10-24"}],"filename":"2024RP0074.pdf","filesize":[{"value":"74 KB"}],"format":"application/pdf","url":{"label":"2024RP0074.pdf","url":"https://mie-u.repo.nii.ac.jp/record/2000984/files/2024RP0074.pdf"},"version_id":"872c5a19-2c06-42e2-bc09-5b990aacac47"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"放射線肺臓炎","subitem_subject_scheme":"Other"},{"subitem_subject":"肺線維症","subitem_subject_scheme":"Other"},{"subitem_subject":"テネイシンC","subitem_subject_scheme":"Other"},{"subitem_subject":"肺癌","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"item_resource_type","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"細胞外マトリックス（テネイシンC）による放射線肺障害の病態解明とその臨床応用","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"細胞外マトリックス（テネイシンC）による放射線肺障害の病態解明とその臨床応用","subitem_title_language":"ja"},{"subitem_title":"Pathophysiology of radiation lung injury by extracellular matrix (tenascin C).","subitem_title_language":"en"}]},"item_type_id":"8","owner":"15","path":["1728958087061"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-10-24"},"publish_date":"2024-10-24","publish_status":"0","recid":"2000984","relation_version_is_last":true,"title":["細胞外マトリックス（テネイシンC）による放射線肺障害の病態解明とその臨床応用"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2024-10-24T01:27:06.202589+00:00"}