{"created":"2024-10-24T02:28:11.193761+00:00","id":2000988,"links":{},"metadata":{"_buckets":{"deposit":"8784dce0-f060-4ae3-a847-3addf43505e0"},"_deposit":{"created_by":15,"id":"2000988","owner":"15","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"2000988"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:02000988","sets":["631:636:1728958087061"]},"author_link":[],"item_8_biblio_info_6":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-05-19","bibliographicIssueDateType":"Issued"}}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"blood oxygenation level-dependent(BOLD)-MRIを用いた検討において、その方法を確立し、胎児発育不全（FGR）では正常妊婦に比べ胎盤の酸素化が低下しており、胎盤病理での胎盤機能障害を反映していることが示唆された。次に、タダラフィルのFGR治療の機序解明のための研究として、FGR症例で、子宮動脈血流量を2D phase contrast (2D PC)-MRIで評価した。正常妊婦と比較して、FGRでは子宮動脈血流量が少なかった。また、タダラフィルを投与したFGR症例においては、正常妊婦と比較し、子宮動脈血流量が増加していることが分かった。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"In the blood oxygenation level-dependent (BOLD)-MRI study, the oxygenation of the placenta was decreased in the FGR compared to the normal pregnant, suggesting that this reflects placental dysfunction in placental pathology. Next, as a study to elucidate the mechanism of tadalafil treatment of FGR, uterine arterial blood flow was evaluated in FGR cases by 2D phase contrast (2D PC)-MRI. Compared to normal pregnant women, uterine arterial blood flow was lower in FGR. In FGR cases treated with tadalafil, uterine arterial blood flow was found to be increased compared to that of normal pregnant.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"2019年度～2022年度科学研究費補助金(若手研究)研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"19K17134","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_31":{"attribute_name":"出版者（ヨミ）","attribute_value_mlt":[{"subitem_text_value":"ミエダイガク"}]},"item_8_text_65":{"attribute_name":"item_8_text_65","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"二井, 理文","creatorNameLang":"ja"},{"creatorName":"Nii, Masafumi","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-10-24"}],"filename":"2024RP0078.pdf","filesize":[{"value":"171 KB"}],"format":"application/pdf","url":{"label":"2024RP0078.pdf","url":"https://mie-u.repo.nii.ac.jp/record/2000988/files/2024RP0078.pdf"},"version_id":"993a668f-18ef-42a4-99a7-3a66b3aec32c"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"FGR","subitem_subject_scheme":"Other"},{"subitem_subject":"BOLD","subitem_subject_scheme":"Other"},{"subitem_subject":"2D PC-MRI","subitem_subject_scheme":"Other"},{"subitem_subject":"胎盤酸素化","subitem_subject_scheme":"Other"},{"subitem_subject":"子宮動脈血流量","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"item_resource_type","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"胎児発育不全妊婦のMRIによる胎盤、胎児の酸素濃度変動測定とタダラフィルの効果","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"胎児発育不全妊婦のMRIによる胎盤、胎児の酸素濃度変動測定とタダラフィルの効果","subitem_title_language":"ja"},{"subitem_title":"Evaluation of placental and fetal oxygen concentration in fetal growth restriction by MRI and effect of tadalafil treatment","subitem_title_language":"en"}]},"item_type_id":"8","owner":"15","path":["1728958087061"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-10-24"},"publish_date":"2024-10-24","publish_status":"0","recid":"2000988","relation_version_is_last":true,"title":["胎児発育不全妊婦のMRIによる胎盤、胎児の酸素濃度変動測定とタダラフィルの効果"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2024-10-24T02:37:12.601886+00:00"}