{"created":"2024-10-28T04:31:53.724404+00:00","id":2001021,"links":{},"metadata":{"_buckets":{"deposit":"6ae63d74-bb11-4075-99cd-6590179ef951"},"_deposit":{"created_by":15,"id":"2001021","owner":"15","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"2001021"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:02001021","sets":["420:724:1728958246114"]},"author_link":[],"control_number":"2001021","item_8_biblio_info_6":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-06-02","bibliographicIssueDateType":"Issued"}}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"微生物や動物細胞等を用いた物質生産技術が注目されており，全世界で関連市場が急速に拡大していくと予想されている．しかしながら，微生物や動物細胞を改変したスマートセルによる物質生産において大量に作製されたスマートセルの分析がボトルネックである．特にこれらスマートセルの培養は不可欠であり，個々の増殖過程を同時にモニタリングする技術が求められている．そこで本研究では微生物や細胞の代謝熱を高感度に測定することができる微小熱量測定法を改良することで振とう培養に対応した最小の微生物増殖測定用セルの開発を行った．さらにこれらセルを複数搭載したスマートセルに対応した微生物増殖測定技術を開発した．","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"Material production technology using microorganisms and animal cells has been attracting attention, and the related market is expected to expand rapidly worldwide. However, since microorganisms and animal cell-modified smart cells are produced in large quantities, their analysis is a bottleneck. In particular, culture of these smart cells is essential, and technology to simultaneously monitor the growth process of each individual cell is required. In this study, we developed the smallest cell for measuring microbial growth compatible with shaking culture by improving a microcalorimetry method that can measure the metabolic heat of microorganisms and animal cells with high sensitivity. Furthermore, we have developed a microbial growth measurement technique for smart cells that are equipped with multiple measurement cells.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"2019年度～2022年度科学研究費補助金(基盤研究(C))研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"19K05161","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_31":{"attribute_name":"出版者（ヨミ）","attribute_value_mlt":[{"subitem_text_value":"ミエダイガク"}]},"item_8_text_65":{"attribute_name":"item_8_text_65","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"三宅, 英雄","creatorNameLang":"ja"},{"creatorName":"Miyake, Hideo","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-10-28"}],"filename":"2024RP0109.pdf","filesize":[{"value":"330 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"2024RP0109.pdf","url":"https://mie-u.repo.nii.ac.jp/record/2001021/files/2024RP0109.pdf"},"version_id":"1bf28122-525d-4510-9bd1-e3789692a10e"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"熱測定","subitem_subject_scheme":"Other"},{"subitem_subject":"微生物","subitem_subject_scheme":"Other"},{"subitem_subject":"増殖","subitem_subject_scheme":"Other"},{"subitem_subject":"スマートセル","subitem_subject_scheme":"Other"},{"subitem_subject":"培養","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"item_resource_type","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"スマートセルに対応した微生物増殖測定技術の開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"スマートセルに対応した微生物増殖測定技術の開発","subitem_title_language":"ja"},{"subitem_title":"Development of microbial growth measurement technology for smart cells","subitem_title_language":"en"}]},"item_type_id":"8","owner":"15","path":["1728958246114"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-10-28"},"publish_date":"2024-10-28","publish_status":"0","recid":"2001021","relation_version_is_last":true,"title":["スマートセルに対応した微生物増殖測定技術の開発"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2024-11-04T23:55:43.109192+00:00"}