{"created":"2025-05-19T05:52:52.228722+00:00","id":2001467,"links":{},"metadata":{"_buckets":{"deposit":"8b792388-8b9f-4bf6-a574-1b8a272d9585"},"_deposit":{"created_by":15,"id":"2001467","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"2001467"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:02001467","sets":["334:608:618:1721969789237"]},"author_link":[],"control_number":"2001467","item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2025-03-25","bibliographicIssueDateType":"Issued"}}]},"item_7_date_granted_59":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2025-03-25"}]},"item_7_degree_grantor_57":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"三重大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"14101","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_7_degree_name_56":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士(医学)"}]},"item_7_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose: Sperm DNA fragmentation (SDF) has recently received attention as a cause of male infertility. However, SDF cannot be fully assessed using conventional semen parameter evaluations alone. Therefore, the authors aimed to elucidate the relationship between SDF and sperm parameters via computer-assisted sperm analysis (CASA) to improve treatment strategies in reproductive medicine.\nMethods: This retrospective observational study analyzed the relationship between sperm parameters assessed by CASA and SDF values determined by the TUNEL assay in 359 patients who visited the Mie University Hospital for infertility treatment. The methodology involved semen analyses covering concentration, motility, and morphology, followed by SDF quantification using the flow cytometry.\nResults: Statistical analysis revealed significant correlations between SDF and various factors, including age, sexual abstinence period, and specific CASA-measured parameters. Notably, lower sperm motility rates and abnormal head dimensions were associated with higher SDF values, indicating that these parameters were predictive of SDF.\nConclusions: This study highlights the importance of sperm motility and head morphology as indicators of SDF, suggesting their usefulness in assessing male fertility. These findings demonstrate the efficacy of detailed sperm analysis, potentially increasing the success rate of assisted reproductive technologies by improving sperm selection criteria.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_7_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"本文 / Department of Obstetrics and Gynecology, Graduate School of Medicine, Mie University, Tsu, Japan","subitem_description_type":"Other"},{"subitem_description":"8p","subitem_description_type":"Other"}]},"item_7_dissertation_number_60":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲医学第2313号"}]},"item_7_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_7_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1002/rmb2.12585","subitem_relation_type_select":"DOI"}}]},"item_7_text_31":{"attribute_name":"出版者（ヨミ）","attribute_value_mlt":[{"subitem_text_value":"ミエダイガク"}]},"item_7_text_65":{"attribute_name":"資源タイプ（三重大）","attribute_value_mlt":[{"subitem_text_value":"Doctoral Dissertation / 博士論文"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAlternatives":[{"creatorAlternative":"Yoshiakwa-Terada, Kento","creatorAlternativeLang":"en"}],"creatorNames":[{"creatorName":"寺田, 堅斗","creatorNameLang":"ja"},{"creatorName":"テラダ, ケント","creatorNameLang":"ja-Kana"},{"creatorName":"Terada, Kento","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"2024DM0336.pdf","filesize":[{"value":"2.95 MB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"2024DM0336.pdf","objectType":"fulltext","url":"https://mie-u.repo.nii.ac.jp/record/2001467/files/2024DM0336.pdf"},"version_id":"ec6b660e-ad79-40c1-ba0e-52fa6e5a49d3"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"abstinence","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"computer-assisted sperm analysis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"sperm DNA fragmentation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"sperm morphology","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"sperm motility","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Age, sexual abstinence duration, sperm morphology, and motility are predictors of sperm DNA fragmentation","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Age, sexual abstinence duration, sperm morphology, and motility are predictors of sperm DNA fragmentation","subitem_title_language":"en"}]},"item_type_id":"7","owner":"15","path":["1721969789237"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2025-05-19"},"publish_date":"2025-05-19","publish_status":"0","recid":"2001467","relation_version_is_last":true,"title":["Age, sexual abstinence duration, sperm morphology, and motility are predictors of sperm DNA fragmentation"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2025-05-20T00:29:58.800650+00:00"}