@article{oai:mie-u.repo.nii.ac.jp:00005565,
 author = {窪田, 三朗 and Kubota, Saburoh S. and 天野, 秀臣 and Amano, Hideomi and 一岡, 衛 and Ichioka, Mamoru and 宮崎, 照雄 and Miyazaki, Teruo and 丹羽, 誠 and Niwa, Makoto},
 journal = {三重大学水産学部研究報告 = Bulletin of the Faculty of Fisheries, Mie University},
 month = {Oct},
 note = {application/pdf, The authors investigated biochemically and histopathologically spontaneous and experimental methemoglobinemia in the Japanese eel (Anguilla japonica). 1. Spontaneous methemoglobinemia. The disease occurred in Japanese eels reared in culturing ponds using a water recirculating system which had high levels of nitrite (7.8～10.5ppm) in the winter of 1980, in Mie Prefecture. Twelve sampled fish had chocolate brown colored blood and liver characteristically. A few of them were accompanied by dropsy and jaundice. The blood of nine fish had high proportions of methemoglobin to total hemoglobin as 33～70%. Histopathological findings were varied with the levels of methemoglobin. In fish having 61～70% of methemoglobin levels, degeneration of erythrocytes in the blood, erythrophagocytosis in the spleen and thrombosis of gill lamellae were distincitive. In fish having 33～47% of methemoglobin levels, degeneration of erythrocytes was mild and hemosiderosis was intensive in the spleen and the kidney. 2. Experimental methemoglobinemia. Twelve eels were exposed to a nitrite concentration of 20, 30 and 40 ppm, using a flow-through system of aquaria, for 31 days. The fish exhibited methemoglobinemia and had 4～66% of methemoglobin to total hemoglobin. They manifested histopathological characteristics similar to those of fish suffering from spontaneous methemoglobinemia. Based on results from this study, it was judged that nitrite poisoning was a representative cause of methemoglobinemia.},
 pages = {149--161},
 title = {ニホンウナギのメトヘモグロビン血症},
 volume = {8},
 year = {1981}
}