@article{oai:mie-u.repo.nii.ac.jp:00005592,
 author = {Miyazaki, Teruo and 宮崎, 照雄 and Nakauchi, Ryosuke and 中内, 良介 and Kubota, Saburoh S. and 窪田, 三朗},
 journal = {三重大学水産学部研究報告 = Bulletin of the Faculty of Fisheries, Mie University},
 month = {Oct},
 note = {application/pdf, Toxicological examinations of oxolinic acid (OA) and nalidixic acid (NA) were performed at overdoses six and twenty times the standard dose in yellowtail, Seriola quenqueradiata. Examined doses of OA were 60 mg and 120 mg / Kg / day and doses of NA were 120 mg and 400 mg /Kg / day. The dosing period was seven days and the recovery period which followed was fourteen days. The side-effects in fish dosed with OA and NA were loss of appetite and dark body discoloration. The effects of OA and NA on the hematology were appearance of macrocytic erythrocytes and occurrence of macrocytic anemia. The effects of OA and NA on the histopathology were fat reduction of hepatocytes and nephrosis, which were severer in fish dosed with NA than OA. The hematological data indicate that both OA and NA inhibit DNA synthesis of erthroblasts of the dosed fish.},
 pages = {15--26},
 title = {Toxicological Examinations of Oxolinic Acid and Nalidixic Acid in Yellowtail},
 volume = {11},
 year = {1984}
}