{"created":"2023-06-19T11:38:09.166247+00:00","id":5741,"links":{},"metadata":{"_buckets":{"deposit":"2fe507d0-9ef9-4696-9e48-34498b100432"},"_deposit":{"created_by":13,"id":"5741","owners":[13],"pid":{"revision_id":0,"type":"depid","value":"5741"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:00005741","sets":["420:421:443:451"]},"author_link":["12605","12606","12607","12608"],"item_4_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1992-03-26","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"34","bibliographicPageStart":"27","bibliographicVolumeNumber":"8","bibliographic_titles":[{"bibliographic_title":"三重大学生物資源学部紀要 = The bulletin of the Faculty of Bioresources, Mie University"}]}]},"item_4_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_4_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The biological activity of water extracts from 29 species of marine algae was investigated and some extracts from the seaweeds were found to possess potential as medical agents. Three extracts showed antitumor effect on B-16 melanoma cells transplanted subcutaneously in mice. One of these extracts, Amphiroa aberrans, in particular, showed high activity (77.4%). Extract of Sargassum patens, S. micracanthum, Gelidium amansii, Gloiophloea okamurai and Gloiopeltis furcata induced the formation of antitumor factors against L929 cells from human HL-60 and murine macrophage hybridoma (MφH) MH6E11 cells. Extracts of S. kjellmanianum, G. amansii and Grateloupia elliptica suppressed the production of these factors in MH6E11 cells activated by lipopolysaccharide. TNF inhibits lipoprotein lipase. Extracts from Ishige okamurai, reverse this inhibition. Six seaweed extracts (3 brown, and 3 red algae) suppressed the thymus cells. Three of them, S. kjellmanianum, G. amansii and G. elliptica, suppressed the activation of MφH, in addition to inhibitioning thymus cell proliferation.","subitem_description_type":"Abstract"}]},"item_4_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学生物資源学部"}]},"item_4_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0915-0471","subitem_source_identifier_type":"PISSN"}]},"item_4_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10073846","subitem_source_identifier_type":"NCID"}]},"item_4_subject_16":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"664","subitem_subject_scheme":"NDC"}]},"item_4_text_18":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Search for Bioactive Substances from Marine Algae"}]},"item_4_text_63":{"attribute_name":"ノート","attribute_value_mlt":[{"subitem_text_value":"Agropedia提供データ"}]},"item_4_text_65":{"attribute_name":"資源タイプ（三重大）","attribute_value_mlt":[{"subitem_text_value":"Departmental Bulletin Paper / 紀要論文"}]},"item_4_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"水越, 貞範","creatorNameLang":"ja"},{"creatorName":"Mizukoshi, Sadanori","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"松岡, 宏芳","creatorNameLang":"ja"},{"creatorName":"Matsuoka, Hiroyoshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"加藤, 文法","creatorNameLang":"ja"},{"creatorName":"Katou, Huminori","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"野田, 宏行","creatorNameLang":"ja"},{"creatorName":"Noda, Hiroyuki","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-18"}],"displaytype":"detail","filename":"AN100738460000803.pdf","filesize":[{"value":"472.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AN100738460000803.pdf","url":"https://mie-u.repo.nii.ac.jp/record/5741/files/AN100738460000803.pdf"},"version_id":"553f08e6-65a8-4674-ba7c-5977d6cbb6ec"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"marine algae","subitem_subject_scheme":"Other"},{"subitem_subject":"bioactive substances","subitem_subject_scheme":"Other"},{"subitem_subject":"antitumor factor","subitem_subject_scheme":"Other"},{"subitem_subject":"tumor necrosis factor","subitem_subject_scheme":"Other"},{"subitem_subject":"lipoprotein lipase","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"海藻成分からの生理活性物質の探索","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"海藻成分からの生理活性物質の探索","subitem_title_language":"ja"}]},"item_type_id":"4","owner":"13","path":["451"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2007-06-06"},"publish_date":"2007-06-06","publish_status":"0","recid":"5741","relation_version_is_last":true,"title":["海藻成分からの生理活性物質の探索"],"weko_creator_id":"13","weko_shared_id":-1},"updated":"2023-10-12T02:43:48.302695+00:00"}