{"created":"2023-06-19T11:38:11.935267+00:00","id":5806,"links":{},"metadata":{"_buckets":{"deposit":"0cd9a702-b8af-4ba7-9155-7eff27e93ee2"},"_deposit":{"created_by":13,"id":"5806","owners":[13],"pid":{"revision_id":0,"type":"depid","value":"5806"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:00005806","sets":["420:421:443:457"]},"author_link":["12903","12904"],"item_4_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1995-03-25","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"156","bibliographicPageStart":"151","bibliographicVolumeNumber":"14","bibliographic_titles":[{"bibliographic_title":"三重大学生物資源学部紀要 = The bulletin of the Faculty of Bioresources, Mie University"}]}]},"item_4_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_4_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The effect of proteins, a polypeptide, and amino acids such as albumin, ε-polylysine and histidine in the depolymerization of hyaluronic acid was examined. All of the proteins, a polypeptide, and amino acids examined supressed the depolymerization with different inhibition ratios. In addition, the inhibition ratio in the depolymerization of hyaluronic acid by D-fructose 6-phosohate - Cu²⁺ differed from that in the depolymerization of hyaluronic acid by hydrogen peroxide. These results suggested that the mode of depolymerization of hyaluronic acid and active oxygen species involved in the reaction were different between the two systems. Imcomplete inhibition of ε-polylysine and lysine in the depolymerization of hyaluronic acid by hydrogen peroxide implied the involvement of some active oxygen species in the reaction.","subitem_description_type":"Abstract"},{"subitem_description":"2価銅イオン存在下でのD-フラクトース 6-リン酸および過酸化水素系によるヒアルロン酸解重合反応に及ぼす蛋白質，ポリペプチドおよぴアミノ酸の影響を研究した。使用した蛋白質，ポリペプチド，アミノ酸全てに，程度に差はあるものの，解重合反応阻害効果が認められた。これらの異なる活性酸素生成系でその阻害率が異なったが，これは発生している活性酸素種が異なるためと考えられる。さらに，ε-ポリリジンとリジンの添加効果\nが0.01％以上で頭打ちになることより，過酸化水素系によるヒアルロン酸解重合反応には複数（2つ以上の意味）の活性酸素種が関与しているものと推察された。","subitem_description_type":"Abstract"}]},"item_4_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学生物資源学部"}]},"item_4_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0915-0471","subitem_source_identifier_type":"PISSN"}]},"item_4_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10073846","subitem_source_identifier_type":"NCID"}]},"item_4_subject_16":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"430","subitem_subject_scheme":"NDC"}]},"item_4_text_18":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"The Effect of Some Proteins, A Peptide, and Amino Acids in the Depolymerization of Hyaluronic Acid by Active Oxygen Species"}]},"item_4_text_63":{"attribute_name":"ノート","attribute_value_mlt":[{"subitem_text_value":"Agropedia提供データ"}]},"item_4_text_65":{"attribute_name":"資源タイプ（三重大）","attribute_value_mlt":[{"subitem_text_value":"Departmental Bulletin Paper / 紀要論文"}]},"item_4_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"佐藤, 郁夫","creatorNameLang":"ja"},{"creatorName":"Sato, Ikuo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"12903","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柏村, 直樹","creatorNameLang":"ja"},{"creatorName":"Kashimura, Naoki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"12904","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-18"}],"displaytype":"detail","filename":"AN100738460001407.pdf","filesize":[{"value":"311.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AN100738460001407.pdf","url":"https://mie-u.repo.nii.ac.jp/record/5806/files/AN100738460001407.pdf"},"version_id":"0e9d59ba-600d-42c0-9093-c1dea5374d72"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"hyaluronic acid","subitem_subject_scheme":"Other"},{"subitem_subject":"depolymerization","subitem_subject_scheme":"Other"},{"subitem_subject":"active oxgen species","subitem_subject_scheme":"Other"},{"subitem_subject":"proteins","subitem_subject_scheme":"Other"},{"subitem_subject":"ε-polylysine","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"活性酸素によるヒアルロン酸の解重合反応に及ぼす二，三の蛋白質，ポリペプチドおよびアミノ酸の影響","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"活性酸素によるヒアルロン酸の解重合反応に及ぼす二，三の蛋白質，ポリペプチドおよびアミノ酸の影響","subitem_title_language":"ja"}]},"item_type_id":"4","owner":"13","path":["457"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2007-05-08"},"publish_date":"2007-05-08","publish_status":"0","recid":"5806","relation_version_is_last":true,"title":["活性酸素によるヒアルロン酸の解重合反応に及ぼす二，三の蛋白質，ポリペプチドおよびアミノ酸の影響"],"weko_creator_id":"13","weko_shared_id":-1},"updated":"2023-10-12T06:05:37.311371+00:00"}