{"created":"2023-06-19T11:38:14.106235+00:00","id":5855,"links":{},"metadata":{"_buckets":{"deposit":"9d105470-f6f1-48f2-8f5d-4fb5db0299f4"},"_deposit":{"created_by":13,"id":"5855","owners":[13],"pid":{"revision_id":0,"type":"depid","value":"5855"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:00005855","sets":["420:421:443:466"]},"author_link":["13204","13205","13206","13207"],"item_4_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1999-12-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"96","bibliographicPageStart":"81","bibliographicVolumeNumber":"23","bibliographic_titles":[{"bibliographic_title":"三重大学生物資源学部紀要 = The bulletin of the Faculty of Bioresources, Mie University"}]}]},"item_4_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_4_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The killer phenomenon is widespread among various genera and species of yeasts. Killer yeasts secrete polypeptides, known as killer factors that kill sensitive strains of yeasts, in their culture medium. Among these factors, HM-1 of Hansenula mrakii IFO 0895 has unique features. It has high stability against heat treatment and is stable in wide a pH range. It also kills a variety of other yeast strains. The killing mechanism and The cell wall receptor of HM-1 have been extensively studied. These studies suggest that HM-1 can be used as an anti-fungal agent. While molecular mechanism of K1 killer factor of Saccharomyces cerevisiae, killer factor of Kluyveromyces lactis and SMKT of Pichia farinosa are also described.","subitem_description_type":"Abstract"},{"subitem_description":"キラー現象は多くの酵母が示す現象である。キラー酵\n母はキラー因子とよばれるタンパク質性の抗菌因子を培\n地中に分泌する。これらキラー因子のなかで，\nHansenula mrakiiのHM－1は，熱安定性，pH安定性\nにおいてきわめて優れている。また，作用する菌株も広\n範囲に及ぶ。HM－1の作用機構は，感受性株の細胞壁グ\nルカン合成酵素の阻害にあり，受容体も細胞表層にある\nことが示されている。これらの特徴を考えると，HM－1\nが新たな抗真菌剤開発のモデルとして期待される。ここ\nでは，その他の主なキラー因子である，S．cerevisiae\nのK1キラー因子，K.lactisのキラー因子，耐塩性のキ\nラー酵母P.farinosaのSMKTについても解説をした。","subitem_description_type":"Abstract"}]},"item_4_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学生物資源学部"}]},"item_4_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0915-0471","subitem_source_identifier_type":"PISSN"}]},"item_4_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10073846","subitem_source_identifier_type":"NCID"}]},"item_4_subject_16":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"465","subitem_subject_scheme":"NDC"}]},"item_4_text_18":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Studies on Yeast Killer Factors and Their Use for Anti‐fungal Agents"}]},"item_4_text_63":{"attribute_name":"ノート","attribute_value_mlt":[{"subitem_text_value":"Agropedia提供データ"}]},"item_4_text_65":{"attribute_name":"資源タイプ（三重大）","attribute_value_mlt":[{"subitem_text_value":"Departmental Bulletin Paper / 紀要論文"}]},"item_4_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"木村, 哲哉","creatorNameLang":"ja"},{"creatorName":"Kimura, Tetsuya","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"苅田, 修一","creatorNameLang":"ja"},{"creatorName":"Karita, Shuichi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"粟冠, 和郎","creatorNameLang":"ja"},{"creatorName":"Sakka, Kazuo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大宮, 邦雄","creatorNameLang":"ja"},{"creatorName":"Omiya, Kunio","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-18"}],"displaytype":"detail","filename":"AN100738460002306.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AN100738460002306.pdf","url":"https://mie-u.repo.nii.ac.jp/record/5855/files/AN100738460002306.pdf"},"version_id":"41e46e07-e018-412c-ac46-5fba9c7b8be6"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Anti-fungal agent","subitem_subject_scheme":"Other"},{"subitem_subject":"Killer factor","subitem_subject_scheme":"Other"},{"subitem_subject":"Hansenula mrakii","subitem_subject_scheme":"Other"},{"subitem_subject":"Saccharomyce cerevisiae","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"酵母のキラー因子研究と抗真菌剤としての応用","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"酵母のキラー因子研究と抗真菌剤としての応用","subitem_title_language":"ja"}]},"item_type_id":"4","owner":"13","path":["466"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2007-05-08"},"publish_date":"2007-05-08","publish_status":"0","recid":"5855","relation_version_is_last":true,"title":["酵母のキラー因子研究と抗真菌剤としての応用"],"weko_creator_id":"13","weko_shared_id":-1},"updated":"2023-10-12T07:44:49.897608+00:00"}