@article{oai:mie-u.repo.nii.ac.jp:00006365,
 author = {小宮, 孝志 and Komiya, Takashi and 山田, 哲也 and Yamada, Tetsuya and 奈良, 省三 and Nara, Shozo and 樋廻, 博重 and Hibasami, Hiroshige},
 journal = {三重大學農學部學術報告 = The bulletin of the Faculty of Agriculture, Mie University},
 month = {Mar},
 note = {application/pdf, Radiosensitization with p-CPG, p-BPG and m-IPG was examined in E. coli B when the bacterial suspension and sensitizers were X-ray irradiated under anaerobic condition. The radiosensitizing lethal effect iucreased in the order of m-IPG≫p-BPG>p-CFG. To elucidate the molecular mechanism of the radiosensitizing activity of m-IPG, the radiosensitizing lethal effect by addition of the radical scavengerss such as KSCN, HCOONa and N₂O and (6-³H)-thymidine incorporation into DNA of E. coli B after irradiation was examined. Only the addition of KSCN enhanced greatly the inhibition effect on DNA synthesis of E. coli B by X-ray irradiation. This effect may be attributed to the reaction of (SCN)-₂ with some enzymic protein, but it was inhibited in the coexistence of m-IPG. The addition of low concentration of HCOONa inhibited greatly the radiosensitizing lethal effect and the inhibiting effect of ³H-thymidine incorporation with m-IPG. However, the addition of high concentration of HCOONa raised the level of the inhibiting effect of ³H-thymidine incorporation to that of the case where only m-IPG is added. This may be attributed to I-₃ resulting from the chain reaction of m-IPG and ･CO-₂. By the addition of only N₂O₂, a great radiosensitizing lethal effect and a large inhibiting effect on DNA synthesis of　E. coli B by X-ray irradiation appeared. However, the latter effect was largely inhibited by the existence of m-IPG.},
 pages = {65--70},
 title = {ハロゲノフェニルグルコシド類の放射線増感に関する研究 : m-ヨードフェニルグルコシドの放射線増感効果に対するラジカル補捉剤の影響},
 volume = {68},
 year = {1984}
}