@article{oai:mie-u.repo.nii.ac.jp:00007095,
 author = {冨樫, 健二 and Togashi, Kenji and 増田, 英成 and Masuda, Hidenari and 住田, 安弘 and Sumida, Yasuhiro and 勝木, 顕 and Katsuki, Akira and 神谷, 齊 and Kamiya, Hitoshi},
 journal = {デサントスポーツ科学},
 month = {Jun},
 note = {application/pdf, It is well known that abdominal visceral fat is closely related to insulin resistance in
adult subjects. But few reports have evaluated the relationship between abdominal fat and
insulin resistance in obese children using MRI or CT scanning. The purpose of this study
was to investigate the sex difference in abdominal fat distribution（AFD）and insulin
resistance in obese children. The subjects were 66 obese children（38 boys, and 28 girls）
with a mean age of 10.9 years（7-17 years）and a mean relative weight（RW）of
152.9%. Abdominal subcutaneous fat（ASF）and visceral fat（AVF）were measured
using L4-L5 CT scanning. The 3-h（Pre, 30, 60, 120, and 180min）oral glucose tolerancetest（OGTT）was performed, and we regarded the insulin area-under-the-curve（AUC）
as an index of insulin resistance. There was no significant difference in ASF between boys
and girls（253.3 vs 268.0cm2），but AVF was significantly larger in boys than in girls
（57.8 vs 43.7cm2: p < 0.05）．The insulin AUC was significantly greater in girls than in
boys（10652.1 vs 6922.3uU min/ml: p < 0.001）．The simple correlation of both ASF and
AVF with insulin AUC in both sexes was significant. After controlling for the total
adiposity（RW）by partial correlation, the relationship between AFD and insulin AUC
disappeared in girls, but remained in boys. These data suggest that total body fat, rather
than abdominal fat, may be the primary determinant of insulin resistance in girls. On the
other hand, in boys the abdominal fat depot, especially AVF, is associated with insulin
resistance independent of total body fat level., 肥満小児におけるメタボリックシンドロームの実態と食事、運動による改善},
 pages = {49--55},
 title = {肥満小児のインスリン抵抗性獲得における内臓脂肪の影響},
 volume = {27},
 year = {2006}
}