{"created":"2023-06-19T11:39:25.864659+00:00","id":7479,"links":{},"metadata":{"_buckets":{"deposit":"99739cfe-653b-4259-bd81-303679d0b8ed"},"_deposit":{"created_by":15,"id":"7479","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"7479"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:00007479","sets":["334:606:607"]},"author_link":[],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1998-08-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"suppl. 1","bibliographicPageEnd":"49","bibliographicPageStart":"45","bibliographicVolumeNumber":"41","bibliographic_titles":[{"bibliographic_title":"耳鼻咽喉科展望"}]}]},"item_10001_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"吸入された粒子の気道への沈着は、粒子の物理的性質によるばかりでなく気道各部位の気流の状態などによっても決定される。空気力学的直径(ADD)から5μm以上の粒子の沈着は慣性衝突により生ずる。慣性衝突によるエアロゾルの沈着はStokes数により決定される。　　　　　　　　　　ADDが8μm以上のエアロゾル粒子の大部分は、とくに最も前方のいわゆる“nasal valve”の部位に沈着する。この部位は鼻軟骨で形成（構築）されており、この部位の断面積は鼻腔の中でも最も小さい。エアロゾル発生装置の鼻アダプターをnasal valve内に挿入することは鼻甲介や鼻道にエアロゾルの沈着を増加させることができるものと考えられる。　　　　　　　　　　　　　　　　副鼻腔へのエアロゾルの沈着は圧勾配を鼻腔と副鼻腔の間に生じさせた場合のみに生じる。大きな圧勾配とはValsalva法、Toynbee法,Polizer法をエアロゾル発生装置により生じた空気圧と合わせて施行することにより得ることができる。ADDが1~10μmの粒子は副鼻腔に沈着することが可能である。","subitem_description_type":"Abstract"},{"subitem_description":"Deposition of inhaled particles in the respiratory tract is determined not only by the physical characteristics of the particles, but also by the nature of the airflow in the various regions. The particles whose aerodynamic diameter (ADD) is more than 5μm are deposited by the inertial impaction. The aerosol deposition by the inertial impaction　is related to Stokers number. Large part of the aerosol  particles with ADD exceeding 8μm are deposited in the nose especially in the most anterior part of the nasal cavity so called \"nasal valve\". The nasal valve is framed by nasal cartilages and  its cross sectional area is the smallest in the nasal cavity, An introduction of a nasal adaptor of an aerosol generator through this region may enhance the aerosol deposition in the nasal turbinate and meatus. The aerosol particles are deposited in the paranasal sinuses only when the pressure gradient is applied between the nasal cavity and the sinuses. A large pressure gradient is obtained by Val salve maneuver, Toynbee or Politzer methods in combination with an air pressure produced by an aerosol generator. The particles with ADD ranging from 1 to 10μm are capable of depositing in the sinuses.","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"耳鼻咽喉科展望会"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN0020828X","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0386-9687","subitem_source_identifier_type":"PISSN"}]},"item_10001_subject_21":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_10001_text_25":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_text_value":"Basic concepts of aerosol therapy in nose and paranasal sinuses"}]},"item_10001_text_70":{"attribute_name":"資源タイプ（三重大）","attribute_value_mlt":[{"subitem_text_value":"Journal Article / 学術雑誌論文"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"間島, 雄一","creatorNameLang":"ja"},{"creatorName":"マジマ, ユウイチ","creatorNameLang":"ja-Kana"}]},{"creatorNames":[{"creatorName":"Majima, Yuichi","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-18"}],"displaytype":"detail","filename":"AN0020828X041s0101.pdf","filesize":[{"value":"626.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AN0020828X041s0101.pdf","url":"https://mie-u.repo.nii.ac.jp/record/7479/files/AN0020828X041s0101.pdf"},"version_id":"9088b068-eae9-487c-83e5-265db705d2d5"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"エアロゾル沈着","subitem_subject_scheme":"Other"},{"subitem_subject":"エアロゾル粒子","subitem_subject_scheme":"Other"},{"subitem_subject":"エアロゾル療法","subitem_subject_scheme":"Other"},{"subitem_subject":"鼻腔","subitem_subject_scheme":"Other"},{"subitem_subject":"副鼻腔","subitem_subject_scheme":"Other"},{"subitem_subject":"aerosol deposition","subitem_subject_scheme":"Other"},{"subitem_subject":"aerosol particle","subitem_subject_scheme":"Other"},{"subitem_subject":"aerosol therapy","subitem_subject_scheme":"Other"},{"subitem_subject":"nose","subitem_subject_scheme":"Other"},{"subitem_subject":"paranasal sinuses","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"エアロゾル療法における基礎的研究の歩み","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"エアロゾル療法における基礎的研究の歩み","subitem_title_language":"ja"}]},"item_type_id":"10001","owner":"15","path":["607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2007-05-10"},"publish_date":"2007-05-10","publish_status":"0","recid":"7479","relation_version_is_last":true,"title":["エアロゾル療法における基礎的研究の歩み"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-10-11T01:56:57.787792+00:00"}