@article{oai:mie-u.repo.nii.ac.jp:00007486, author = {竹内, 万彦 and Takeuchi, kazuhiko and 鈴村, 恵理 and Suzumura, Eri and 平田, 圭甫 and Hirata, Keisuke and 間島, 雄一 and Majima, Yuichi and 坂倉, 康夫 and Sakakura, Yasuo}, issue = {9}, journal = {Therapeutic Research}, month = {Sep}, note = {application/pdf, 慢性副鼻腔炎の手術時に上顎洞粘膜と上顎洞貯留液を同時に得られた15例で,粘膜の電気特性と貯留液のレオロジー的性質を測定し,両者間の関係を検討した。上顎洞粘膜の電位差,短絡電流はアミロリド(I)投与により有意に低下した。上顎洞貯留液の動的弾性率・粘性率は正常鼻汁より高く,慢性副鼻腔炎鼻汁と同等な値を示した。Iによる短絡電流阻害率と上顎洞貯留液の弾性率・粘性率の間に正相関を認めた, Chronic paranasal sinusitis is a chronic inflammatory disease wih fluid retention, most frequently in the maxillary sinus. We measured both viscoelasticity of maxillary sinus fluid and bioelectric properties of maxillary mucosa from fifteen patients with chronic sinusitis in an attempt to correlate the mucus viscoelasticity with bioelectric properties. The viscoelasticity was measured with an oscillating sphere magnetic rheometer within 24 hours after sampling. Potential difference and short circuit current of maxillary mucosa mounted in Ussing chambers, were measured before and after exposure of mucosal surface to amiloride. Viscoelasticity of maxillary fluid was as high as that of nasal mucus in the patients with chronic sinusitis. Both elasticity and viscosity showed significant positive correlation with per cent inhibition of shortcircuit current by amiloride. Our results indicate that ion transport process plays an important role in the determination of viscoelasticity of maxillary sinus fluid in chronic sinusitis.}, pages = {3067--3071}, title = {慢性副鼻腔炎粘膜のイオン輸送と貯留液の粘弾性}, volume = {11}, year = {1990} }