{"created":"2023-06-19T11:39:27.761496+00:00","id":7523,"links":{},"metadata":{"_buckets":{"deposit":"393cfceb-bca8-45ec-bfe9-40d8970a307f"},"_deposit":{"created_by":15,"id":"7523","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"7523"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:00007523","sets":["334:606:607"]},"author_link":["18092","18093","18094","18095","18096","18097","18098","18099","18100","18101","18102"],"control_number":"7523","item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-02-20","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"330","bibliographicPageStart":"327","bibliographicVolumeNumber":"71","bibliographic_titles":[{"bibliographic_title":"Circulation journal : official journal of the Japanese Circulation Society"}]}]},"item_10001_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background :  Tenascin-C (TN-C), an extracellular matrix glycoprotein, is specifically expressed at high levels during embryonic development, but not in the adult heart. TN-C reappears at sites of inflammatory tissue remodeling or wound healing under various pathologic conditions, such as acute myocardial infarction, acute myocarditis, and some cases of cardiomyopathy. Therefore, the expression of TN-C might be useful for detecting the clinical characteristics of, and ventricular remodeling in, dilated cardiomyopathy (DCM). Methods and Results :  Circulating serum TN-C levels in 107 patients with DCM were measured using an ELISA kit. Clinical data were also assessed by Pearson's or Spearman's correlation analysis to estimate correlations between variables. Serum TN-C levels in DCM patients were higher than those in normal controls (p<0.001). TNC levels showed a significantly positive correlation with New York Heart Association functional class (p<0.001), B-type natriuretic peptide level (p<0.001), cardiothoracic ratio on chest X-ray (p<0.01), left ventricular end-diastolic diameter (p<0.05) and left ventricular end-systolic diameter (p<0.01), and a significantly negative correlation with left ventricular ejection fraction (p<0.01). Conclusions :  The findings suggest that increased serum TN-C levels indicate the severity of heart failure, left ventricular dysfunction and remodeling in patients with DCM.","subitem_description_type":"Abstract"}]},"item_10001_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"テネイシンCを分子標的とした心筋梗塞後リモデリング治療法開発のための基礎的研究","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Japanese Circulation Society"}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1253/circj.71.327","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_42":{"attribute_name":"関係URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"http://www.jstage.jst.go.jp/article/circj/71/3/327/_pdf"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"http://ci.nii.ac.jp/naid/110006224198/"}]}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11591968","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13469843","subitem_source_identifier_type":"PISSN"}]},"item_10001_subject_21":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_10001_text_43":{"attribute_name":"著作の一部","attribute_value_mlt":[{"subitem_text_value":"http://hdl.handle.net/10076/7743"}]},"item_10001_text_68":{"attribute_name":"ノート","attribute_value_mlt":[{"subitem_text_value":"出版者版電子ジャーナルあり"}]},"item_10001_text_70":{"attribute_name":"資源タイプ（三重大）","attribute_value_mlt":[{"subitem_text_value":"Journal Article / 学術雑誌論文"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Terasaki, Fumio","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18092","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Okamoto, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18093","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Onishi, Katsuya","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18094","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sato, Akira","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18095","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shimomura, Hiroaki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18096","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsukada, Bin","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18097","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Imanaka-Yoshida, Kyoko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18098","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiroe, Michiaki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18099","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshida, Toshimichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18100","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kitaura, Yasushi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18101","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kitabatake, Akira","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18102","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-18"}],"displaytype":"detail","filename":"30A5777.pdf","filesize":[{"value":"5.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"30A5777.pdf","url":"https://mie-u.repo.nii.ac.jp/record/7523/files/30A5777.pdf"},"version_id":"87189e3d-c511-4265-aa87-d585fd79f4d7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Dilated cardiomyopathy","subitem_subject_scheme":"Other"},{"subitem_subject":"Heart failure","subitem_subject_scheme":"Other"},{"subitem_subject":"Tenascin-C","subitem_subject_scheme":"Other"},{"subitem_subject":"Ventricular remodeling","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Higher serum Tenascin-C levels reflect the severity of heart failure, left ventricular dysfunction and remodeling in patients with dilated cardiomyopathy","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Higher serum Tenascin-C levels reflect the severity of heart failure, left ventricular dysfunction and remodeling in patients with dilated cardiomyopathy","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"15","path":["607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2007-12-25"},"publish_date":"2007-12-25","publish_status":"0","recid":"7523","relation_version_is_last":true,"title":["Higher serum Tenascin-C levels reflect the severity of heart failure, left ventricular dysfunction and remodeling in patients with dilated cardiomyopathy"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-10-23T02:00:15.860817+00:00"}