@article{oai:mie-u.repo.nii.ac.jp:00007528,
 author = {西城, 隆一郎 and Saijo, Ryuichiro and 間島, 雄一 and Majima, Yuichi and 兵, 昇 and Hyo, Noboru and 高野, 頌 and Takano, Hiroshi and 國貞, 智弘 and Kunisada, Tomohiro},
 issue = {suppl. 1},
 journal = {耳鼻咽喉科展望. 補冊},
 month = {Aug},
 note = {application/pdf, 鼻内副鼻腔手術患者を対象として下甲介先端、上顎洞内、後部篩骨洞へのエアロゾル到達濃度の検討を超音波ネブライザーとジェットネブライザーを用いて行った。結果は、下甲介先端、上顎洞内、後部篩骨洞の順に高い薬物濃度を示し、後部篩骨洞においても副鼻腔炎起炎菌に対して充分な薬物濃度を示した。また、ジェットネブライザーを用いた方が超音波ネブライザーを用いた方より高い薬物濃度を示した。, Aerosol depositions in the maxillary and ethmoidal sinuses were evaluated in 6 patients who underwent endoscopic sinus surgery. One percent Cefmenoxime hydrochloride (CMX) was the drug seleced to be administered by nebulization. The aerosol was generated at a flow rate of 3l/min by a jet-type nebulizer, Azwell Nescojet AZ-11, and the diameter of the aerosolized particles ranged from 5 to 15μm. The diameters of the aerosolized particles generated by an ultrasonic-type nebulizer, Omron NE-U12, were distributed in the range of 1 to 5μm, and the aerosol was generated at the flow rate of 17l/min. In the maxillary sinus, the aerosolized particles generated by the jet-type nebulizer were deposited to a greater extent than those generated by the ultrasonic-type nebulizer. The aerosol deposition pattern in the ethmoidal sinus was similar to that in the maxillary sinus. The concentrations of CMX in each sinus were adove the MICs for the pathogens implicated in sinusitis. The results suggest that aerosol therapy could be useful as a postopeartive treatment adjunct for sinusitis.},
 pages = {11--14},
 title = {鼻内手術後副鼻腔へのエアロゾル到達濃度の検討ー上顎洞、篩骨洞についてー},
 volume = {43},
 year = {2000},
 yomi = {サイジョウ, リュウイチロウ and マジマ, ユウイチ and ヒョウ, ノボル and タカノ, ヒロシ and クニサダ, トモヒロ}
}