{"created":"2023-06-19T11:39:28.187506+00:00","id":7533,"links":{},"metadata":{"_buckets":{"deposit":"75c23e94-f8f8-4d49-8932-d3a1b03365da"},"_deposit":{"created_by":15,"id":"7533","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"7533"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:00007533","sets":["334:606:607"]},"author_link":["18192","18193"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1998-10-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"227","bibliographicPageStart":"221","bibliographicVolumeNumber":"20","bibliographic_titles":[{"bibliographic_title":"環境変異原研究"}]}]},"item_10001_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"It is well known that various kinds of active oxygen and other radical species, alkylating agents and UV can induce site-specific DNA damage. Sequence-specificity of DNA damage is determined by oxidation potential of radical species, DNA recognition of alkylating agents, ionization potential and molecular electrostatic potential of DNA. Cells have repair mechanisms that correct such site-specific DNA damage. However, when these defenses are oversaturated, such as under conditions of highly oxidative stress, the DNA damage has an increased miscoding potential. In this paper, we review mechanisms of the site-specific DNA damage and its association with the carcinogenicity process and with the carcinostatic effect.","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本環境変異原学会"}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"日本環境変異原学会","subitem_rights_resource":"本文データは学協会の許諾に基づきCiNiiから複製したものである"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN1006217X","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0910-0865","subitem_source_identifier_type":"PISSN"}]},"item_10001_subject_21":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_10001_text_25":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_text_value":"Role of sequence-specificity of DNA damage"}]},"item_10001_text_41":{"attribute_name":"シリーズ","attribute_value_mlt":[{"subitem_text_value":"http://ci.nii.ac.jp/naid/110001713575/"}]},"item_10001_text_70":{"attribute_name":"資源タイプ（三重大）","attribute_value_mlt":[{"subitem_text_value":"Journal Article / 学術雑誌論文"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"及川, 伸二","creatorNameLang":"ja"},{"creatorName":"Oikawa, Shinji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18192","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"川西, 正祐","creatorNameLang":"ja"},{"creatorName":"Kawanishi, Shosuke","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18193","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-18"}],"displaytype":"detail","filename":"30A6627.pdf","filesize":[{"value":"713.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"30A6627.pdf","url":"https://mie-u.repo.nii.ac.jp/record/7533/files/30A6627.pdf"},"version_id":"d262afaf-806a-43e6-bc05-e8e74b68c9b5"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"oxygen radical","subitem_subject_scheme":"Other"},{"subitem_subject":"UV","subitem_subject_scheme":"Other"},{"subitem_subject":"alkylating agent","subitem_subject_scheme":"Other"},{"subitem_subject":"DNA damage","subitem_subject_scheme":"Other"},{"subitem_subject":"sequence-specificity","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"DNA損傷における塩基配列特異性とその意義","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"DNA損傷における塩基配列特異性とその意義","subitem_title_language":"ja"}]},"item_type_id":"10001","owner":"15","path":["607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2008-03-03"},"publish_date":"2008-03-03","publish_status":"0","recid":"7533","relation_version_is_last":true,"title":["DNA損傷における塩基配列特異性とその意義"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-10-11T05:06:54.781469+00:00"}