{"created":"2023-06-19T11:39:48.721940+00:00","id":7998,"links":{},"metadata":{"_buckets":{"deposit":"c434bb48-9a9e-4e2e-a513-6bbd19eb18fd"},"_deposit":{"created_by":15,"id":"7998","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"7998"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:00007998","sets":["334:627:1692670315782"]},"author_link":["19422","19423"],"item_8_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-05-21","bibliographicIssueDateType":"Issued"}}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"中胚葉或いは神経堤由来細胞を蛍光標識できるマウスを用いて歯の間葉の大部分が神経堤細胞に、骨髄の間葉細胞の半分が中胚葉由来及び神経堤に由来する細胞からなることを明らかにした。また、間葉系幹細胞の検出法であるColony-Forming Unit Fibroblast(CFU-F)アッセイにより歯のCFU-F形成細胞は主に神経堤に、骨髄のCFU-F形成細胞は神経堤のみならず、中胚葉に由来する細胞からなることを明らかにした。また歯髄の間葉細胞が骨髄の間葉細胞と同様にB細胞や破骨細胞の分化を支持する能力を持つ事を見いだした。","subitem_description_type":"Abstract"},{"subitem_description":"By using transgenic mouse which enabled us to trace NC-derived or mesodermal cells, we showed that dental mesenchyme was composed of mainly NC-derived cells, whereas half of bone marrow(BM) mesenchyme was composed of cells other than NC-derived and mesodermal cells. Furthremore, a colony-forming unit-fibroblast(CFU-F) assay indicated that CFU-Fs in the dental pulp are derived from NC, and BM are derived from both NC and mesodermal cells. Furthermore, we showed that dental mesenchyme supported the differentiation of B lymphocytes and osteoclasts.","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"平成22~23年度科学研究費補助金(挑戦的萌芽研究)研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"21659422","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_18":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_text_value":"Analysis of the origin and properties of dental and bone marrow mesenchymal stem cells by using mice to label NC-derived and mesodermal cells"}]},"item_8_text_65":{"attribute_name":"資源タイプ（三重大）","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"山崎, 英俊","creatorNameLang":"ja"},{"creatorName":"YAMAZAKI, Hidetoshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山根, 利之","creatorNameLang":"ja"},{"creatorName":"YAMANE, Toshiyuki","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-18"}],"displaytype":"detail","filename":"30K16757.pdf","filesize":[{"value":"341.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"30K16757.pdf","url":"https://mie-u.repo.nii.ac.jp/record/7998/files/30K16757.pdf"},"version_id":"3b4cd7b2-b57e-4578-98bf-3c6620a92ceb"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"神経堤細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"中胚葉","subitem_subject_scheme":"Other"},{"subitem_subject":"間葉系幹細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"歯髄細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"骨髄間葉系細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"象牙芽細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"胚性幹細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"細胞系譜追跡","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"神経堤と中胚葉を標識できるマウスを用いた歯髄及び骨髄幹細胞の起源と性状の解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"神経堤と中胚葉を標識できるマウスを用いた歯髄及び骨髄幹細胞の起源と性状の解明","subitem_title_language":"ja"}]},"item_type_id":"8","owner":"15","path":["1692670315782"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-03-10"},"publish_date":"2014-03-10","publish_status":"0","recid":"7998","relation_version_is_last":true,"title":["神経堤と中胚葉を標識できるマウスを用いた歯髄及び骨髄幹細胞の起源と性状の解明"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-11-06T04:41:20.632632+00:00"}