{"created":"2023-06-19T11:39:49.318116+00:00","id":8012,"links":{},"metadata":{"_buckets":{"deposit":"a0e5f017-f718-4fb4-92da-b5e41ec8ed10"},"_deposit":{"created_by":15,"id":"8012","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"8012"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:00008012","sets":["334:627:1692670245812"]},"author_link":["19480","19481","19482","19483"],"item_8_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-04-14","bibliographicIssueDateType":"Issued"}}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"パニック障害においてモノアミン関連酵素(MAOA)と血清コレステロール値との関連が見出され(特に男性)、発症年齢とパニック発作時の症状数など重症度との関連や家族内発症が影響が示された。その他、合併症としては広場恐怖やうつ病の合併が疾患としての重症度を高めることも示された。診断マーカー候補の一つとして光トポグラフィー(NIRS)を用いた前頭葉機能の検討を行い、前頭前皮質内側部についてパニック障害のTrait marker、罹患者のみで賦活の低下を認めた前頭葉外側部についてはState marker となる可能性が示された。またCOMTVal158Met 多型において左前頭葉での賦活の相違が認められ、疾患群における自律神経症状との対応が考えられた。","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"平成19~20年度科学研究費補助金(基盤研究(C))研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"19591349","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_18":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_text_value":"Development of biological marker of panic disorder"}]},"item_8_text_65":{"attribute_name":"資源タイプ（三重大）","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"谷井, 久志","creatorNameLang":"ja"},{"creatorName":"TANII, Hisashi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"19480","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"西村, 幸香","creatorNameLang":"ja"},{"creatorName":"NISHIMURA, Yukika","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"19481","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中川, 雅紀","creatorNameLang":"ja"},{"creatorName":"NAKAGAWA, Masanori","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"19482","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"樫本, 香苗","creatorNameLang":"ja"},{"creatorName":"KASHIMOTO, Kanae","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"19483","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-18"}],"displaytype":"detail","filename":"30K16613.pdf","filesize":[{"value":"290.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"30K16613.pdf","url":"https://mie-u.repo.nii.ac.jp/record/8012/files/30K16613.pdf"},"version_id":"c145424b-f8f1-43c4-87fe-7ee3db882467"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"パニック障害","subitem_subject_scheme":"Other"},{"subitem_subject":"診断マーカー","subitem_subject_scheme":"Other"},{"subitem_subject":"コレステロール","subitem_subject_scheme":"Other"},{"subitem_subject":"前頭葉機能","subitem_subject_scheme":"Other"},{"subitem_subject":"COMTVal158Met 多型","subitem_subject_scheme":"Other"},{"subitem_subject":"Trait marker","subitem_subject_scheme":"Other"},{"subitem_subject":"State marker","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"パニック障害の生物学的マーカーの開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"パニック障害の生物学的マーカーの開発","subitem_title_language":"ja"}]},"item_type_id":"8","owner":"15","path":["1692670245812"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-03-10"},"publish_date":"2014-03-10","publish_status":"0","recid":"8012","relation_version_is_last":true,"title":["パニック障害の生物学的マーカーの開発"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-11-06T02:39:35.820947+00:00"}