{"created":"2023-06-19T11:39:50.965953+00:00","id":8051,"links":{},"metadata":{"_buckets":{"deposit":"fc85be72-978a-48b0-9aee-9e5cb3f26780"},"_deposit":{"created_by":15,"id":"8051","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"8051"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:00008051","sets":["334:627:1692670356714"]},"author_link":[],"item_8_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-05-28","bibliographicIssueDateType":"Issued"}}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ホールセルパッチクランプ法を用いた電気生理学的実験により、ヒト嗅細胞における嗅覚情報伝達機構を分子レベルで解明し、体内の神経系組織で唯一生体外に直接晒されている嗅神経細胞が、体外環境、特に嗅覚障害の原因と考えられている物理的、化学的変化に対して、どのように影響を受けるかを確認することを目的に本研究を施行した。　双極性細胞を中心に特徴的な細胞を顕微鏡用ビデオカメラを使用し撮影した。線毛はほとんど確認できなかったが樹状突起やその先端膨張部を確認した。　ホールセルパッチクランプ法で、ヒト嗅細胞から膜電流を記録することに成功した。ヒト嗅細胞が他の種の嗅細胞と同様の電位依存性を示すことを明らかにした。","subitem_description_type":"Abstract"},{"subitem_description":"To reveal signal transduction system of human olfactory receptor cells, we tried to record membrane potential of the olfactory receptor cells obtained from human using whole cell patch clamp method. We succeeded to record membrane potential of human olfactory receptor cells using the method and found that characteristics of the human olfactory receptor cells are similar to those of other animals that were reported previously.","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"2010年度～2013年度科学研究費補助金(基盤研究(C))研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"22591898","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_18":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_text_value":"Signal transduction system of human olfactory receptor cells"}]},"item_8_text_65":{"attribute_name":"資源タイプ（三重大）","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小林, 正佳","creatorNameLang":"ja"},{"creatorName":"KOBAYASHI, Masayoshi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"倉橋, 隆","creatorNameLang":"ja"},{"creatorName":"KURAHASHI, Takashi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"竹内, 裕子","creatorNameLang":"ja"}],"familyNames":[{"familyName":"TAKEUCHI, Hiroko","familyNameLang":"en"}]},{"creatorNames":[{"creatorName":"山本, 哲朗","creatorNameLang":"ja"},{"creatorName":"YAMAMOTO, Tetsuro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"竹内, 万彦","creatorNameLang":"ja"},{"creatorName":"TAKEUCHI, Kazuhiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"玉利, 健悟","creatorNameLang":"ja"},{"creatorName":"TAMARI, Kengo","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-18"}],"displaytype":"detail","filename":"30K17504.pdf","filesize":[{"value":"372.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"30K17504.pdf","url":"https://mie-u.repo.nii.ac.jp/record/8051/files/30K17504.pdf"},"version_id":"7dbd8d94-99d1-419c-8137-b67db8fd8c47"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"嗅覚","subitem_subject_scheme":"Other"},{"subitem_subject":"嗅細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"ヒト","subitem_subject_scheme":"Other"},{"subitem_subject":"パッチクランプ","subitem_subject_scheme":"Other"},{"subitem_subject":"免疫染色","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"ヒト嗅細胞における嗅覚情報伝達機構の解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ヒト嗅細胞における嗅覚情報伝達機構の解明","subitem_title_language":"ja"}]},"item_type_id":"8","owner":"15","path":["1692670356714"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2016-01-15"},"publish_date":"2016-01-15","publish_status":"0","recid":"8051","relation_version_is_last":true,"title":["ヒト嗅細胞における嗅覚情報伝達機構の解明"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-11-07T04:16:15.001859+00:00"}