{"created":"2023-06-19T11:39:52.599078+00:00","id":8089,"links":{},"metadata":{"_buckets":{"deposit":"d665d5c6-02dd-40e9-bc80-2082dc87daf7"},"_deposit":{"created_by":15,"id":"8089","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"8089"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:00008089","sets":["334:627:1692670376097"]},"author_link":["19897"],"item_8_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2015-05-20","bibliographicIssueDateType":"Issued"}}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"食道癌例対象として、がんワクチン「CHP-MAGE-A4蛋白ワクチン」及び「CHP-NY-ESO-1蛋白ワクチン」の臨床試験を行い、採取された血液検体（血清、リンパ球成分）、腫瘍組織を用いて、腫瘍組織での抗原発現、血清を用いた抗原蛋白パネルでの網羅的マイクロアレイ反応解析、MAGE-A4、NY-ESO-1抗原蛋白に対するELISA解析で抗体反応を行い、投与ワクチン抗原以外への免疫反応拡散現象を評価した。","subitem_description_type":"Abstract"},{"subitem_description":"Clinical trials of cancer vaccine, including CHP-MAGE-A4 protein vaccine and CHP-NY-ESO-1 protein vaccine, were conducted for esophageal cancer patients. Tumor samples were analyzed for tumor antigen expressions. Serum samples of pre-vaccine and post-vaccine time points were analyzed for protein microarray reactions and ELISA of MAGE-A4 and NY-ESO-1 antigens. We assessed immune-spreading phenomenon across other antigens that were not immunized.","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"2012年度～2014年度科学研究費補助金(基盤研究(C))研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"24591939","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_18":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_text_value":"Spreading immune-reactions in esophageal cancer patients who were given cancer vaccine and whose tumors co-express additional antigens"}]},"item_8_text_65":{"attribute_name":"資源タイプ（三重大）","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"影山, 愼一","creatorNameLang":"ja"},{"creatorName":"KAGEYAMA, Shinichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"19897","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-18"}],"displaytype":"detail","filename":"30K17882.pdf","filesize":[{"value":"360.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"30K17882.pdf","url":"https://mie-u.repo.nii.ac.jp/record/8089/files/30K17882.pdf"},"version_id":"c4ca008d-f5e5-4964-ae0f-01d2f3f67e79"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"がんワクチン","subitem_subject_scheme":"Other"},{"subitem_subject":"食道癌","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"食道癌に同時発現している癌抗原分子間でのがんワクチン前後の免疫拡大とその意義","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"食道癌に同時発現している癌抗原分子間でのがんワクチン前後の免疫拡大とその意義","subitem_title_language":"ja"}]},"item_type_id":"8","owner":"15","path":["1692670376097"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-01-13"},"publish_date":"2017-01-13","publish_status":"0","recid":"8089","relation_version_is_last":true,"title":["食道癌に同時発現している癌抗原分子間でのがんワクチン前後の免疫拡大とその意義"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-11-07T04:40:47.954234+00:00"}