{"created":"2023-06-19T11:39:54.593210+00:00","id":8136,"links":{},"metadata":{"_buckets":{"deposit":"86da5ffc-bf1e-4afd-addd-0350af0fa3f8"},"_deposit":{"created_by":15,"id":"8136","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"8136"},"status":"published"},"_oai":{"id":"oai:mie-u.repo.nii.ac.jp:00008136","sets":["631:636:1692684589395"]},"author_link":["20198","20193","20194","20195"],"item_8_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-05-14","bibliographicIssueDateType":"Issued"}}]},"item_8_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"20198","nameIdentifierScheme":"WEKO"}]}]},"item_8_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"直腸癌化学放射線療法後の遠隔転移誘導メカニズムをさまざまな角度からin vivo、in vitroで検証した。(1)抗癌剤耐性関連因子、(2) Angiogenesis関連因子、(3) Stem cell関連因子、(4)ケモカイン関連因子、(5)上皮間葉移行(EMT)関連因子、(6)間質関連、(7)その他について解析を行った結果、これらすべてにおいて、直腸癌遠隔転移再発に関与することが示唆された。すなわち、直腸癌化学放射線療法後の生存率向上にはより一層の多面的アプローチによるトランスレーショナルリサーチが必要である。","subitem_description_type":"Abstract"},{"subitem_description":"We investigated the mechanism of distant recurrence in rectal cancer patients after preoperative chemoradiotherapy to improve the prognosis of patients with advanced rectal cancer further. The mechanism were analyzed from several viewpoints including 1) anti-cancer agents, 2) angiogenesis, 3) stemcell, 4) chemokines, 5) epitherial-mesenchymal transition(EMT), 6) cancer-stromal interaction, et al. Our study suggested that these all factors were associated with distant recurrence with several interactions. Therefore, we need to investigate the mechanism from various angles further, to control distant recurrence in rectal cancer patients after preoperative chemoradiotherapy.","subitem_description_type":"Abstract"}]},"item_8_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"平成21~23年度科学研究費補助金(基盤研究(C))研究成果報告書","subitem_description_type":"Other"}]},"item_8_description_64":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_description":"21591723","subitem_description_type":"Other"}]},"item_8_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"三重大学"}]},"item_8_text_18":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_text_value":"Mechanism of distant recurrence in rectal cancer patients after preoperative chemoradiotherapy"}]},"item_8_text_65":{"attribute_name":"資源タイプ（三重大）","attribute_value_mlt":[{"subitem_text_value":"Kaken / 科研費報告書"}]},"item_8_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"井上, 靖浩","creatorNameLang":"ja"},{"creatorName":"INOUE, Yasuhiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"楠, 正人","creatorNameLang":"ja"},{"creatorName":"KUSUNOKI, Masato","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"三木, 誓雄","creatorNameLang":"ja"},{"creatorName":"MIKI, Chikao","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-18"}],"displaytype":"detail","filename":"39K16828.pdf","filesize":[{"value":"362.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"39K16828.pdf","url":"https://mie-u.repo.nii.ac.jp/record/8136/files/39K16828.pdf"},"version_id":"310bcb04-e8a4-4841-844b-0a9a06819fe0"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"直腸癌","subitem_subject_scheme":"Other"},{"subitem_subject":"化学放射線療法","subitem_subject_scheme":"Other"},{"subitem_subject":"遠隔転移","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"化学放射線療法後の直腸癌遠隔転移誘導メカニズムの解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"化学放射線療法後の直腸癌遠隔転移誘導メカニズムの解明","subitem_title_language":"ja"}]},"item_type_id":"8","owner":"15","path":["1692684589395"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-03-10"},"publish_date":"2014-03-10","publish_status":"0","recid":"8136","relation_version_is_last":true,"title":["化学放射線療法後の直腸癌遠隔転移誘導メカニズムの解明"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-11-13T00:40:32.251455+00:00"}