Koi herpesvirus（KHV）disease causes mass mortalities in the world, however there is no ways to treat this disease. We tried passive immunization by intramuscular injections with anti KHV-IgY （Immunoglobulin Yolk＝Egg yolk antibody）in order to protect koi from KHV infection. Injected IgY containing anti KHV-IgY was absorbed into the blood serum at high concentration in day 1 after three injections, which was maintained to day 14. The immunized fish were challenged by immersion with cultured KHV in day 1 and were protected from KHV infection at 95％ RPS. The results indicate that passive immunization using anti KHV-Ig Y is effective to protect koi from KHV.
雑誌名
三重大学大学院生物資源学研究科紀要
巻
40
ページ
29 - 33
発行年
2014-03-01
書誌レコードID
AA12234310
フォーマット
application/pdf
著者版フラグ
publisher
その他のタイトル
Studies on Passive Immunization with Anti viral IgY-I : Passive Immunization with Anti Koi Herpesvirus IgY in Koi
抗ウイルス鶏卵抗体（IgY）による受動免疫効果に関する研究-I : コイにおける抗コイヘルペスウイルスIgYの受動免疫効果
50C16967.pdf
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