WEKO3
アイテム
{"_buckets": {"deposit": "584b4582-5dde-4983-83b8-6cab7a653dc9"}, "_deposit": {"created_by": 13, "id": "5842", "owners": [13], "pid": {"revision_id": 0, "type": "depid", "value": "5842"}, "status": "published"}, "_oai": {"id": "oai:mie-u.repo.nii.ac.jp:00005842", "sets": ["464"]}, "author_link": ["13124", "13125", "13126", "13127"], "item_4_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1999-01-05", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "85", "bibliographicPageStart": "73", "bibliographicVolumeNumber": "21", "bibliographic_titles": [{"bibliographic_title": "三重大学生物資源学部紀要 = The bulletin of the Faculty of Bioresources, Mie University"}]}]}, "item_4_description_14": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_4_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "We investigated the effects of poly (ADP - ribose) polymerase (PARP) inhibitors and\nNAD on the apoptosis induced by Actinomycin D in human promyelomonocytic\nleukemia cells HL - 60. As the results, the apoptosis was repressed by various PARP\ninhibitors especially by 3 - aminobenzamide ( 3 – ABA ), which is a potent inhibitor forPARP reaction. On the contrary, 3-ABA was no more inhibitory in a cell-free apoptosissystem. This result suggests that the inhibitory effect of 3 - ABA is effective only before apoptotic cytosol is made up in the cells, i.e., in an early stage of the apoptotic process. But NAD inhibited the apoptosis in the same system depending on NAD concentration. So the inhibition of apoptosis by NAD may be concerned in a later step of apoptosis.", "subitem_description_type": "Abstract"}]}, "item_4_publisher_30": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "三重大学生物資源学部"}]}, "item_4_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0915-0471", "subitem_source_identifier_type": "PISSN"}]}, "item_4_source_id_9": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN10073846", "subitem_source_identifier_type": "NCID"}]}, "item_4_subject_16": {"attribute_name": "日本十進分類法", "attribute_value_mlt": [{"subitem_subject": "493", "subitem_subject_scheme": "NDC"}]}, "item_4_text_18": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_text_language": "ja", "subitem_text_value": "ヒト白血病細胞HL-60においてアクチノマイシンDで誘導されるアポトーシスに及ぼすポリ(ADP-リボース)ポリメラーゼ阻害剤とNADの影響"}]}, "item_4_text_65": {"attribute_name": "資源タイプ(三重大)", "attribute_value_mlt": [{"subitem_text_value": "Departmental Bulletin Paper / 紀要論文"}]}, "item_4_version_type_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "緒方, 進", "creatorNameLang": "ja"}, {"creatorName": "Ogata, Shin", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "13124", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "野中, 洋志", "creatorNameLang": "ja"}, {"creatorName": "Nonaka, Hiroshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "13125", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "奥村, 克純", "creatorNameLang": "ja"}, {"creatorName": "Okumura, Katsuzumi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "13126", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "田口, 寛", "creatorNameLang": "ja"}, {"creatorName": "Taguchi, Hiroshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "13127", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-02-18"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "50C12504.pdf", "filesize": [{"value": "2.1 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 2100000.0, "url": {"label": "50C12504.pdf", "url": "https://mie-u.repo.nii.ac.jp/record/5842/files/50C12504.pdf"}, "version_id": "e709194e-1bcb-42b8-a003-0c1dbbdfa9a6"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "poly (ADP-ribose) polymerase", "subitem_subject_scheme": "Other"}, {"subitem_subject": "NAD", "subitem_subject_scheme": "Other"}, {"subitem_subject": "apoptosis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Actinomycin D", "subitem_subject_scheme": "Other"}, {"subitem_subject": "HL-60", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Effects of poly (ADP-ribose) polymerase inhibitors and NAD on the apoptosis induced by actinomycin D in human leukemia cells HL-60", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Effects of poly (ADP-ribose) polymerase inhibitors and NAD on the apoptosis induced by actinomycin D in human leukemia cells HL-60", "subitem_title_language": "en"}]}, "item_type_id": "4", "owner": "13", "path": ["464"], "permalink_uri": "http://hdl.handle.net/10076/10588", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2010-03-18"}, "publish_date": "2010-03-18", "publish_status": "0", "recid": "5842", "relation": {}, "relation_version_is_last": true, "title": ["Effects of poly (ADP-ribose) polymerase inhibitors and NAD on the apoptosis induced by actinomycin D in human leukemia cells HL-60"], "weko_shared_id": -1}
Effects of poly (ADP-ribose) polymerase inhibitors and NAD on the apoptosis induced by actinomycin D in human leukemia cells HL-60
http://hdl.handle.net/10076/10588
http://hdl.handle.net/10076/10588d26122be-e2bf-4cb1-9686-3da7ef619e45
名前 / ファイル | ライセンス | アクション |
---|---|---|
50C12504.pdf (2.1 MB)
|
|
Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2010-03-18 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Effects of poly (ADP-ribose) polymerase inhibitors and NAD on the apoptosis induced by actinomycin D in human leukemia cells HL-60 | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | poly (ADP-ribose) polymerase | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | NAD | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | apoptosis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Actinomycin D | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | HL-60 | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
緒方, 進
× 緒方, 進× 野中, 洋志× 奥村, 克純× 田口, 寛 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We investigated the effects of poly (ADP - ribose) polymerase (PARP) inhibitors and NAD on the apoptosis induced by Actinomycin D in human promyelomonocytic leukemia cells HL - 60. As the results, the apoptosis was repressed by various PARP inhibitors especially by 3 - aminobenzamide ( 3 – ABA ), which is a potent inhibitor forPARP reaction. On the contrary, 3-ABA was no more inhibitory in a cell-free apoptosissystem. This result suggests that the inhibitory effect of 3 - ABA is effective only before apoptotic cytosol is made up in the cells, i.e., in an early stage of the apoptotic process. But NAD inhibited the apoptosis in the same system depending on NAD concentration. So the inhibition of apoptosis by NAD may be concerned in a later step of apoptosis. |
|||||
書誌情報 |
三重大学生物資源学部紀要 = The bulletin of the Faculty of Bioresources, Mie University 巻 21, p. 73-85, 発行日 1999-01-05 |
|||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0915-0471 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10073846 | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
日本十進分類法 | ||||||
主題Scheme | NDC | |||||
主題 | 493 | |||||
その他のタイトル | ||||||
ja | ||||||
ヒト白血病細胞HL-60においてアクチノマイシンDで誘導されるアポトーシスに及ぼすポリ(ADP-リボース)ポリメラーゼ阻害剤とNADの影響 | ||||||
出版者 | ||||||
出版者 | 三重大学生物資源学部 | |||||
資源タイプ(三重大) | ||||||
Departmental Bulletin Paper / 紀要論文 |