| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2024-06-06 |
| タイトル |
|
|
タイトル |
A Combination of Amide Proton Transfer, Tumor Blood Flow, and Apparent Diffusion Coefficient Histogram Analysis Is Useful for Differentiating Malignant from Benign Intracranial Tumors in Young Patients: A Preliminary Study |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
amide proton transfer |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
pseudocontinuous arterial spin labeling |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
apparent diffusion coefficient |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
pediatric brain tumor |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
histogram analysis |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Tanaka, Fumine
Maeda, Masayuki
Nakayama, Ryohei
Inoue, Katsuhiro
Kishi, Seiya
Kogue, Ryota
Umino, Maki
Kitano, Yotaro
Obara, Makoto
Sakuma, Hajime
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Purpose: To evaluate the amide proton transfer (APT), tumor blood flow (TBF), and apparent diffusion coefficient (ADC) combined diagnostic value for differentiating intracranial malignant tumors (MTs) from benign tumors (BTs) in young patients, as defined by the 2021World Health Organization classification of central nervous system tumors. Methods: Fifteen patients with intracranial MTs and 10 patients with BTs aged 0–30 years underwent MRI with APT, pseudocontinuous arterial spin labeling (pCASL), and diffusion-weighted imaging. All tumors were evaluated through the use of histogram analysis and the Mann–Whitney U test to compare 10 parameters for each sequence between the groups. The diagnostic performance was evaluated using receiver operating characteristic (ROC) curve analysis. Results: The APT maximum, mean, 10th, 25th, 50th, 75th, and 90th percentiles were significantly higher in MTs than in BTs; the TBF minimum (min) was significantly lower in MTs than in BTs; TBF kurtosis was significantly higher in MTs than in BTs; the ADC min, 10th, and 25th percentiles were significantly lower in MTs than in BTs (all p < 0.05). The APT 50th percentile (0.900), TBF min (0.813), and ADC min (0.900) had the highest area under the curve (AUC) values of the parameters in each sequence. The AUC for the combination of these three parameters was 0.933. Conclusions: The combination of APT, TBF, and ADC evaluated through histogram analysis may be useful for differentiating intracranial MTs from BTs in young patients. |
|
言語 |
en |
| 書誌情報 |
Diagnostics
巻 14,
号 12,
発行日 2024-06-12
|
| ISSN |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2075-4418 |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.3390/diagnostics14121236 |
| フォーマット |
|
|
内容記述タイプ |
Other |
|
内容記述 |
application/pdf |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 出版者 |
|
|
出版者 |
MDPI |
| 資源タイプ（三重大） |
|
|
値 |
Journal Article / 学術雑誌論文 |
2024JA0003.pdf (3.4 MB)
