Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2014-05-15 |
タイトル |
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タイトル |
Secretogranin II and its Derivative Peptide, Manserin,are Differentially Localized in Purkinje Cells and Unipolar Brush Cells in the Rat Cerebellum. |
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言語 |
en |
言語 |
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言語 |
eng |
キーワード |
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主題Scheme |
Other |
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主題 |
Cerebellum |
キーワード |
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主題Scheme |
Other |
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主題 |
Chromogranin |
キーワード |
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主題Scheme |
Other |
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主題 |
Manserin |
キーワード |
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主題Scheme |
Other |
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主題 |
Neuropeptide |
キーワード |
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主題Scheme |
Other |
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主題 |
Secretogranin |
キーワード |
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主題Scheme |
Other |
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主題 |
Unipolar brush cell |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
著者 |
Ohkawara, Takeshi
Oyabu, Akiko
Ida-Eto, Michiru
Tashiro, Yasura
Tano, Kaori
Nasu, Fumio
Narita, Naoko
Narita, Masaaki
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抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
The cerebellum has long been recognized as the primary center of motor coordination in the central nervous system. Cerebellar neuropeptides have been postulated to be involved in such motor coordination, though this role is not fully understood. We herein investigated the localization of novel neuropeptide, "manserin" in the adult rat cerebellum. Punctate signals of manserin immunoreactivity were observed in the granular layer of the rat cerebellum. Manserin signals were also observed in the fibers and fiber terminals in the granular layer as well as the molecular layer. Manserin did not localize in Purkinje cells. Interestingly, cerebellar manserin was preferentially colocalized with unipolar brush cells, a class of excitatory granular layer interneuron, which are known to be involved in vestibullocerebellar functions. These results indicate that manserin plays pivotal roles in the cerebellar functions. |
書誌情報 |
International Journal of Peptide Research and Therapeutics
巻 17,
号 3,
p. 193-199,
発行日 2011-09-01
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ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
1573-3149 |
DOI |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
10.1007/s10989-011-9257-9 |
権利 |
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権利情報 |
Copyright © Springer, Part of Springer Science+Business Media |
フォーマット |
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内容記述タイプ |
Other |
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内容記述 |
application/pdf |
著者版フラグ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
出版者 |
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出版者 |
Springer Netherlands |
関係URI |
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関連名称 |
http://link.springer.com/article/10.1007/s10989-011-9257-9 |
資源タイプ(三重大) |
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値 |
Journal Article / 学術雑誌論文 |